MeSH Browser

MeSH Heading: Hereditary Sensory and Autonomic Neuropathies
Tree Number(s): C10.500.250; C10.574.500.493; C10.668.829.800.175; C16.131.666.310; C16.320.400.415
Unique ID: D009477
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009477
Annotation: do not confuse with HEREDITARY SENSORY AND MOTOR NEUROPATHY; note entry terms for HSAN types: HSAN TYPE III see DYSAUTONOMIA, FAMILIAL is also available
Scope Note: A group of inherited disorders characterized by degeneration of dorsal root and autonomic ganglion cells, and clinically by loss of sensation and autonomic dysfunction. There are five subtypes. Type I features autosomal dominant inheritance and distal sensory involvement. Type II is characterized by autosomal inheritance and distal and proximal sensory loss. Type III is DYSAUTONOMIA, FAMILIAL. Type IV features insensitivity to pain, heat intolerance, and mental deficiency. Type V is characterized by a selective loss of pain with intact light touch and vibratory sensation. (From Joynt, Clinical Neurology, 1995, Ch51, pp142-4)
Entry Version: HEREDITARY SENSORY AUTONOMIC NEUROPATHIES
Entry Term(s): Acroosteolysis, Giaccai Type; Acroosteolysis, Neurogenic; Congenital Insensitivity to Pain with Anhidrosis; Familial Dysautonomia, Type 2; Familial Dysautonomia, Type II; Giaccai Type Acroosteolysis; HSAN; HSAN (Hereditary Sensory Autonomic Neuropathy); HSAN 1; HSAN 4; HSAN 5; HSAN I; HSAN IV; HSAN Type I; HSAN Type II; HSAN Type IV; HSAN Type V; HSAN V; HSAN2; HSAN5; HSANII; HSN Type I; HSN Type II; Hereditary Sensory And Autonomic Neuropathy IV; Hereditary Sensory Autonomic Neuropathy, Type 1; Hereditary Sensory Autonomic Neuropathy, Type 2; Hereditary Sensory Autonomic Neuropathy, Type 4; Hereditary Sensory Autonomic Neuropathy, Type 5; Hereditary Sensory Neuropathy Type 1; Hereditary Sensory Neuropathy Type I; Hereditary Sensory Neuropathy Type Ia; Hereditary Sensory Radicular Neuropathy; Hereditary Sensory Radicular Neuropathy, Recessive Form; Hereditary Sensory and Autonomic Neuropathy 4; Hereditary Sensory and Autonomic Neuropathy Type 1; Hereditary Sensory and Autonomic Neuropathy Type 2; Hereditary Sensory and Autonomic Neuropathy Type I; Hereditary Sensory and Autonomic Neuropathy Type II; Hereditary Sensory and Autonomic Neuropathy Type IV; Hereditary Sensory and Autonomic Neuropathy Type V; Hereditary Sensory and Autonomic Neuropathy, Type 4; Hereditary Sensory and Autonomic Neuropathy, Type 5; Insensitivity to Pain with Anhidrosis, Congenital; Insensitivity to Pain, Congenital, with Anhidrosis; Neurogenic Acroosteolysis; Neuropathies, Hereditary Sensory and Autonomic; Neuropathy Hereditary Sensory Radicular, Autosomal Dominant; Neuropathy Hereditary Sensory and Autonomic Type 1; Neuropathy, Congenital Sensory; Neuropathy, Congenital Sensory, with Anhidrosis; Neuropathy, Hereditary Sensory And Autonomic, Type I; Neuropathy, Hereditary Sensory And Autonomic, Type V; Neuropathy, Hereditary Sensory Radicular, Autosomal Dominant; Neuropathy, Hereditary Sensory Radicular, Autosomal Recessive; Neuropathy, Hereditary Sensory, Type I; Neuropathy, Progressive Sensory, Of Children; Pain Insensitivity with Anhidrosis, Congenital; Sensory Neuropathy, Hereditary; Sensory and Autonomic Neuropathies, Hereditary
Previous Indexing: Peripheral Nerve Diseases (1966-1978); Peripheral Nerves (1966-1978); Sensation (1966-1978)
See Also: Pain Insensitivity, Congenital
Public MeSH Note: 2000; see NEUROPATHIES, HEREDITARY SENSORY AND AUTONOMIC 1989-1999; see NEUROPATHY, HEREDITARY SENSORY 1979-1988
History Note: 2000(1989); use NEUROPATHY, HEREDITARY SENSORY 1979-1988
Date Established: 1979/01/01
Date of Entry: 1999/11/08
Revision Date: 2018/06/30

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Nervous System Diseases [C10]
- Nervous System Malformations [C10.500]

Nervous System Diseases [C10]
- Neurodegenerative Diseases [C10.574]
  - Heredodegenerative Disorders, Nervous System [C10.574.500]

Nervous System Diseases [C10]
- Neuromuscular Diseases [C10.668]
  - Peripheral Nervous System Diseases [C10.668.829]
    - Polyneuropathies [C10.668.829.800]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Congenital Abnormalities [C16.131]
  - Nervous System Malformations [C16.131.666]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Heredodegenerative Disorders, Nervous System [C16.320.400]

Hereditary Sensory and Autonomic Neuropathies Preferred

Concept UI: M0014743
Scope Note: A group of inherited disorders characterized by degeneration of dorsal root and autonomic ganglion cells, and clinically by loss of sensation and autonomic dysfunction. There are five subtypes. Type I features autosomal dominant inheritance and distal sensory involvement. Type II is characterized by autosomal inheritance and distal and proximal sensory loss. Type III is DYSAUTONOMIA, FAMILIAL. Type IV features insensitivity to pain, heat intolerance, and mental deficiency. Type V is characterized by a selective loss of pain with intact light touch and vibratory sensation. (From Joynt, Clinical Neurology, 1995, Ch51, pp142-4)
Terms: Hereditary Sensory and Autonomic Neuropathies Preferred Term
Term UI T028251
Date06/07/1988
LexicalTag NON
ThesaurusID UNK (19XX); HSAN (Hereditary Sensory Autonomic Neuropathy)
Term UI T365295
Date11/08/1999
LexicalTag ABX
ThesaurusID NLM (2000); HSAN
Term UI T028250
Date06/07/1988
LexicalTag ABB
ThesaurusID UNK (19XX); Sensory and Autonomic Neuropathies, Hereditary
Term UI T028252
Date06/07/1988
LexicalTag NON
ThesaurusID UNK (19XX); Neuropathies, Hereditary Sensory and Autonomic
Term UI T028253
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1979)

Hereditary Sensory Radicular Neuropathy Narrower

HSAN Type IV Narrower

Hereditary Sensory and Autonomic Neuropathy Type II Narrower

Hereditary Sensory and Autonomic Neuropathy Type V Narrower

Hereditary Sensory Neuropathy Type I Narrower

Sensory Neuropathy, Hereditary Narrower

Hereditary Sensory and Autonomic Neuropathies MeSH Descriptor Data 2025