MeSH Browser

MeSH Heading: Nitracrine
Tree Number(s): D03.633.300.046.250.650
Unique ID: D009564
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009564
Scope Note: Acridine antineoplastic agent used in mammary and ovarian tumors. It inhibits RNA synthesis.
Entry Term(s): C-283; Ledakrin
Pharm Action: Antineoplastic Agents
Nucleic Acid Synthesis Inhibitors
Registry Numbers: 712MLZ30SB; 0
Related Numbers: 4533-39-5
CAS Type 1 Name: 1,3-Propanediamine, N,N-dimethyl-N'-(1-nitro-9-acridinyl)-
Previous Indexing: Acridines (1971-1974); Dimethylamines (1973-1974); Nitro Compounds (1972-1974)
Public MeSH Note: 91; was see under AMINOACRIDINES 1985-90; was C 283 see under AMINOACRIDINES 1981-84; was C 283 see under ACRIDINES 1975-80
Online Note: use NITRACRINE to search C 283 1975-84
History Note: 91(85); was see under AMINOACRIDINES 1985-90; was C 283 see under AMINOACRIDINES 1981-84; was C 283 see under ACRIDINES 1975-80
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Nitracrine MeSH Descriptor Data 2025