MeSH Browser

MeSH Heading: Quinacrine
Tree Number(s): D03.633.300.046.250.760
Unique ID: D011796
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011796
Scope Note: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
Entry Term(s): Acrichine; Atabrine; Atebrin; Mepacrine; Quinacrine Dihydrochloride; Quinacrine Dihydrochloride, Dihydrate; Quinacrine Dihyrochloride, (R)-Isomer; Quinacrine Dihyrochloride, (S)-Isomer; Quinacrine Dimesylate; Quinacrine Hydrochloride; Quinacrine Monoacetate; Quinacrine Monohydrochloride; Quinacrine Monomesylate; Quinacrine, (+-)-Isomer; Quinacrine, (R)-Isomer; Quinacrine, (S)-Isomer
Pharm Action: Anticestodal Agents
Antimalarials
Antinematodal Agents
Antineoplastic Agents
Enzyme Inhibitors
Related Numbers: 130-42-7; 130-43-8; 139345-02-1; 139345-03-2; 316-05-2; 56100-41-5; 56100-42-6; 6151-30-0; 66777-81-9; 69-05-6; 78901-94-7; 83-89-6; G6242H2NAA
CAS Type 1 Name: 1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-
NLM Classification #: QV 258
Public MeSH Note: CHINACRIN was see QUINACRINE 1977-93
Online Note: use QUINACRINE to search CHINACRIN 1977-93
History Note: CHINACRIN was see QUINACRINE 1977-93
Date Established: 1960/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, Fused-Ring [D03.633]
  - Heterocyclic Compounds, 3-Ring [D03.633.300]
    - Acridines [D03.633.300.046]
      - Aminoacridines [D03.633.300.046.250]
        
        Acridine Orange [D03.633.300.046.250.150]
        
        Acriflavine [D03.633.300.046.250.177]
        
        Aminacrine [D03.633.300.046.250.200]
        
        Amsacrine [D03.633.300.046.250.225]
        
        Ethacridine [D03.633.300.046.250.450]
        
        Nitracrine [D03.633.300.046.250.650]
        
        Proflavine [D03.633.300.046.250.720]
        
        Quinacrine [D03.633.300.046.250.760]
        
        Quinacrine Mustard [D03.633.300.046.250.760.750]
        
        Tacrine [D03.633.300.046.250.900]

Quinacrine Preferred

Concept UI: M0018330
Related Numbers: 130-42-7; 130-43-8; 139345-02-1; 139345-03-2; 316-05-2; 56100-41-5; 56100-42-6; 6151-30-0; 66777-81-9; 69-05-6; 78901-94-7; 83-89-6; G6242H2NAA
Scope Note: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
Terms: Quinacrine Preferred Term
Term UI T034842
Date01/01/1999
LexicalTag NON
ThesaurusID; Atebrin
Term UI T034840
Date11/20/1980
LexicalTag NON
ThesaurusID UNK (19XX); Mepacrine
Term UI T034841
Date03/30/1974
LexicalTag NON
ThesaurusID

Acrichine Narrower

Quinacrine Monohydrochloride Narrower

Atabrine Narrower

Quinacrine Dimesylate Narrower

Quinacrine Dihyrochloride, (S)-Isomer Narrower

Quinacrine Dihyrochloride, (R)-Isomer Narrower

Quinacrine Dihydrochloride, Dihydrate Narrower

Quinacrine, (+-)-Isomer Narrower

Quinacrine Dihydrochloride Narrower

Quinacrine Monoacetate Narrower

Quinacrine, (R)-Isomer Narrower

Quinacrine Monomesylate Narrower

Quinacrine, (S)-Isomer Narrower

Quinacrine MeSH Descriptor Data 2025