MeSH Browser

MeSH Heading: Masoprocol
Tree Number(s): D02.455.426.559.389.140.450.582; D02.455.426.559.389.657.166.550
Unique ID: D009637
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009637
Scope Note: A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils.
Entry Term(s): (R*,S*)-4,4'-(2,3-Dimethylbutane-1,4-diyl)bispyrocatechol; Actinex; Dihydronorguaiaretic Acid; Nordihydroguaiaretic Acid; Nordihydroguaiaretic Acid, (R*,S*)-Isomer; meso-Nordihydroguaiaretic Acid
Pharm Action: Antioxidants
Lipoxygenase Inhibitors
Cyclooxygenase Inhibitors
Related Numbers: 27686-84-6; 500-38-9
CAS Type 1 Name: 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-
Previous Indexing: Catechols (1966-1986)
Public MeSH Note: 2014; see NORDIHYDROGUAIARETIC ACID 1991-2013; see CATECHOLS 1987-1990
History Note: 2014(1987)
Date Established: 1991/01/01
Date of Entry: 1986/04/09
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0014961
Related Numbers: 27686-84-6; 500-38-9
Scope Note: A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils.
Terms: Masoprocol Preferred Term
Term UI T028669
Date05/25/1995
LexicalTag NON
ThesaurusID; Dihydronorguaiaretic Acid
Term UI T028665
Date04/09/1986
LexicalTag NON
ThesaurusID UNK (19XX); meso-Nordihydroguaiaretic Acid
Term UI T028667
Date05/25/1995
LexicalTag NON
ThesaurusID; Nordihydroguaiaretic Acid
Term UI T028664
Date01/01/1999
LexicalTag NON
ThesaurusID; Nordihydroguaiaretic Acid, (R*,S*)-Isomer
Term UI T360164
Date09/13/1999
LexicalTag NON
ThesaurusID NLM (1999); (R*,S*)-4,4'-(2,3-Dimethylbutane-1,4-diyl)bispyrocatechol
Term UI T837023
Date02/06/2013
LexicalTag NON
ThesaurusID NLM (2014)

Masoprocol MeSH Descriptor Data 2025