Because of a lapse in government funding, the information on this
website may not be up to date, transactions submitted via the
website may not be processed, and the agency may not be able to
respond to inquiries until appropriations are enacted. The NIH
Clinical Center (the research hospital of NIH) is open. For more
details about its operating status, please visit
cc.nih.gov. Updates
regarding government operating status and resumption of normal
operations can be found at
opm.gov.
Paget Disease, Extramammary MeSH Descriptor Data 2026
neoplastic; coordinate with precoordinated organ/neoplasm term
Scope Note
A rare cutaneous neoplasm that occurs in the elderly. It develops more frequently in women and predominantly involves apocrine gland-bearing areas, especially the vulva, scrotum, and perianal areas. The lesions develop as erythematous scaly patches that progress to crusted, pruritic, erythematous plaques. The clinical differential diagnosis includes squamous cell carcinoma in situ and superficial fungal infection. It is generally thought to be an adenocarcinoma of the epidermis, from which it extends into the contiguous epithelium of hair follicles and eccrine sweat ducts. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1478)
Entry Version
PAGET DIS EXTRAMAMMARY
Entry Term(s)
Extra-Mammary Paget Disease
Extra-Mammary Paget's Disease
Extramammary Paget Disease
Extramammary Paget's Disease
Paget Disease Extramammary
Paget Disease, Extra-Mammary
Paget's Disease, Extra-Mammary
Paget's Disease, Extramammary
Public MeSH Note
2010; see PAGET'S DISEASE, EXTRAMAMMARY 1994-2009, see PAGET'S DISEASE, EXTRA-MAMMARY 1963-1993
A rare cutaneous neoplasm that occurs in the elderly. It develops more frequently in women and predominantly involves apocrine gland-bearing areas, especially the vulva, scrotum, and perianal areas. The lesions develop as erythematous scaly patches that progress to crusted, pruritic, erythematous plaques. The clinical differential diagnosis includes squamous cell carcinoma in situ and superficial fungal infection. It is generally thought to be an adenocarcinoma of the epidermis, from which it extends into the contiguous epithelium of hair follicles and eccrine sweat ducts. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1478)