Parabens MeSH Descriptor Data 2025

MeSH Heading: Parabens
Tree Number(s): D02.241.223.100.300.460; D02.241.511.390.460; D02.455.426.559.389.127.281.460; D02.455.426.559.389.657.410.460
Unique ID: D010226
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D010226
Scope Note: Methyl, propyl, butyl, and ethyl esters of p-hydroxybenzoic acid. They have been approved by the FDA as antimicrobial agents for foods and pharmaceuticals. (From Hawley's Condensed Chemical Dictionary, 11th ed, p872)
Entry Term(s): 4-Hydroxybenzoic Acids; Paraben; para-Hydroxybenzoic Acids
Pharm Action: Food Preservatives
Preservatives, Pharmaceutical
Previous Indexing: Benzoates (1966-1970)
Public MeSH Note: 72; METHYLPARABEN was heading 1963-71
Online Note: use PARABENS to search METHYLPARABEN 1966-71
History Note: 72(71); METHYLPARABEN was heading 1963-71
Date Established: 1972/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

Organic Chemicals [D02]
- Carboxylic Acids [D02.241]
  - Acids, Carbocyclic [D02.241.223]
    - Benzoates [D02.241.223.100]
      - Hydroxybenzoates [D02.241.223.100.300]
        
        Depsides [D02.241.223.100.300.100]
        
        Gallic Acid [D02.241.223.100.300.200]
        
        3-Hydroxyanthranilic Acid [D02.241.223.100.300.300]
        
        Hydroxybenzoate Ethers [D02.241.223.100.300.350]
        
        Hydroxymercuribenzoates [D02.241.223.100.300.400]
        
        Pactamycin [D02.241.223.100.300.450]
        
        Parabens [D02.241.223.100.300.460]
        
        Salicylates [D02.241.223.100.300.595]

Organic Chemicals [D02]
- Carboxylic Acids [D02.241]
  - Hydroxy Acids [D02.241.511]
    - Hydroxybenzoates [D02.241.511.390]

Organic Chemicals [D02]
- Hydrocarbons [D02.455]
  - Hydrocarbons, Cyclic [D02.455.426]
    - Hydrocarbons, Aromatic [D02.455.426.559]
      - Benzene Derivatives [D02.455.426.559.389]
        
        Benzoates [D02.455.426.559.389.127]
        
        Hydroxybenzoates [D02.455.426.559.389.127.281]
        
        Depsides [D02.455.426.559.389.127.281.100]
        
        Gallic Acid [D02.455.426.559.389.127.281.200]
        
        Hydroxybenzoate Ethers [D02.455.426.559.389.127.281.350]
        
        Hydroxymercuribenzoates [D02.455.426.559.389.127.281.400]
        
        Pactamycin [D02.455.426.559.389.127.281.450]
        
        Parabens [D02.455.426.559.389.127.281.460]
        
        Salicylates [D02.455.426.559.389.127.281.595]

Organic Chemicals [D02]
- Hydrocarbons [D02.455]
  - Hydrocarbons, Cyclic [D02.455.426]
    - Hydrocarbons, Aromatic [D02.455.426.559]
      - Benzene Derivatives [D02.455.426.559.389]
        
        Phenols [D02.455.426.559.389.657]
        
        Hydroxybenzoates [D02.455.426.559.389.657.410]
        
        Depsides [D02.455.426.559.389.657.410.100]
        
        Gallic Acid [D02.455.426.559.389.657.410.200]
        
        Hydroxymercuribenzoates [D02.455.426.559.389.657.410.400]
        
        Pactamycin [D02.455.426.559.389.657.410.450]
        
        Parabens [D02.455.426.559.389.657.410.460]
        
        Salicylates [D02.455.426.559.389.657.410.595]

Parabens Preferred

4-Hydroxybenzoic Acids Related

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