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Pentoxifylline MeSH Descriptor Data 2025


MeSH Heading
Pentoxifylline
Tree Number(s)
D03.633.100.759.758.824.651.700
Unique ID
D010431
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D010431
Scope Note
A METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.
Entry Term(s)
Agapurin
BL-191
Oxpentifylline
Pentoxil
Torental
Trental
Pharm Action
Phosphodiesterase Inhibitors
Platelet Aggregation Inhibitors
Radiation-Protective Agents
Vasodilator Agents
Free Radical Scavengers
Related Numbers
6493-05-6
CAS Type 1 Name
1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-
NLM Classification #
QV 107
Previous Indexing
Xanthines (1972-1976)
Public MeSH Note
91; see THEOBROMINE 1977-90
History Note
91(77)
Date Established
1991/01/01
Date of Entry
1976/04/16
Revision Date
2016/05/31
Pentoxifylline Preferred
Trental Narrower
Agapurin Narrower
Torental Narrower
BL-191 Narrower
Pentoxil Narrower
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