Physostigmine MeSH Descriptor Data 2025

MeSH Heading: Physostigmine
Tree Number(s): D02.241.081.251.583.682; D03.132.436.545; D03.633.100.473.402.545; D03.633.100.496.500.500.545
Unique ID: D010830
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D010830
Scope Note: A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.
Entry Term(s): Eserine
Pharm Action: Cholinesterase Inhibitors
Miotics
Related Numbers: 57-47-6
CAS Type 1 Name: Pyrrolo(2,3-b)indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, methylcarbamate (ester), (3aS-cis)-
NLM Classification #: QV 124
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Organic Chemicals [D02]
- Carboxylic Acids [D02.241]
  - Acids, Acyclic [D02.241.081]
    - Carbamates [D02.241.081.251]
      - Phenylcarbamates [D02.241.081.251.583]
        
        Carbofuran [D02.241.081.251.583.166]
        
        Chlorpropham [D02.241.081.251.583.177]
        
        Felbamate [D02.241.081.251.583.366]
        
        Methiocarb [D02.241.081.251.583.555]
        
        Methocarbamol [D02.241.081.251.583.577]
        
        Physostigmine [D02.241.081.251.583.682]
        
        Propoxur [D02.241.081.251.583.788]
        
        Pyridinolcarbamate [D02.241.081.251.583.799]
        
        Rivastigmine [D02.241.081.251.583.899]

Heterocyclic Compounds [D03]
- Alkaloids [D03.132]
  - Indole Alkaloids [D03.132.436]

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, Fused-Ring [D03.633]
  - Heterocyclic Compounds, 2-Ring [D03.633.100]
    - Indoles [D03.633.100.473]
      - Indole Alkaloids [D03.633.100.473.402]
        
        Carbolines [D03.633.100.473.402.111]
        
        Harmala Alkaloids [D03.633.100.473.402.222]
        
        Lyngbya Toxins [D03.633.100.473.402.511]
        
        Oxindoles [D03.633.100.473.402.528]
        
        Physostigmine [D03.633.100.473.402.545]
        
        Psilocybin [D03.633.100.473.402.613]
        
        Secologanin Tryptamine Alkaloids [D03.633.100.473.402.681]
        
        Staurosporine [D03.633.100.473.402.750]

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, Fused-Ring [D03.633]
  - Heterocyclic Compounds, 2-Ring [D03.633.100]
    - Indolizines [D03.633.100.496]
      - Indolizidines [D03.633.100.496.500]
        
        Indole Alkaloids [D03.633.100.496.500.500]
        
        Harmala Alkaloids [D03.633.100.496.500.500.384]
        
        Lyngbya Toxins [D03.633.100.496.500.500.448]
        
        Oxindoles [D03.633.100.496.500.500.511]
        
        Physostigmine [D03.633.100.496.500.500.545]
        
        Psilocybin [D03.633.100.496.500.500.613]
        
        Secologanin Tryptamine Alkaloids [D03.633.100.496.500.500.681]
        
        Staurosporine [D03.633.100.496.500.500.750]

Physostigmine Preferred

Eserine Narrower

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