Progesterone MeSH Descriptor Data 2025

MeSH Heading: Progesterone
Tree Number(s): D04.210.500.745.745.654.829; D06.472.334.734.623; D06.472.334.851.687.750
Unique ID: D011374
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011374
Scope Note: The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.
Entry Term(s): Pregnenedione; Progesterone, (13 alpha,17 alpha)-(+-)-Isomer; Progesterone, (17 alpha)-Isomer; Progesterone, (9 beta,10 alpha)-Isomer
Pharm Action: Progestins
Related Numbers: 2000-66-0; 2755-10-4; 57-83-0; 59952-90-8
CAS Type 1 Name: Pregn-4-ene-3,20-dione
NLM Classification #: WP 530
See Also: Receptors, Progesterone
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Polycyclic Compounds [D04]
- Fused-Ring Compounds [D04.210]
  - Steroids [D04.210.500]
    - Pregnanes [D04.210.500.745]
      - Pregnenes [D04.210.500.745.745]
        
        Pregnenediones [D04.210.500.745.745.654]
        
        Aldosterone [D04.210.500.745.745.654.062]
        
        Budesonide [D04.210.500.745.745.654.105]
        
        Corticosterone [D04.210.500.745.745.654.237]
        
        Cortodoxone [D04.210.500.745.745.654.252]
        
        Desoxycorticosterone [D04.210.500.745.745.654.339]
        
        Flurandrenolone [D04.210.500.745.745.654.473]
        
        Flurogestone Acetate [D04.210.500.745.745.654.485]
        
        Gestonorone Caproate [D04.210.500.745.745.654.527]
        
        Halcinonide [D04.210.500.745.745.654.570]
        
        Hydrocortisone [D04.210.500.745.745.654.600]
        
        Progesterone [D04.210.500.745.745.654.829]
        
        Algestone [D04.210.500.745.745.654.829.025]
        
        20-alpha-Dihydroprogesterone [D04.210.500.745.745.654.829.100]
        
        Hydroxyprogesterones [D04.210.500.745.745.654.829.395]

Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
- Hormones [D06.472]
  - Gonadal Hormones [D06.472.334]
    - Corpus Luteum Hormones [D06.472.334.734]
      - Progesterone [D06.472.334.734.623]
      - Relaxin [D06.472.334.734.769]

Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
- Hormones [D06.472]
  - Gonadal Hormones [D06.472.334]
    - Gonadal Steroid Hormones [D06.472.334.851]
      - Progesterone Congeners [D06.472.334.851.687]
        
        Pregnenolone [D06.472.334.851.687.500]
        
        Progesterone [D06.472.334.851.687.750]
        
        5-alpha-Dihydroprogesterone [D06.472.334.851.687.750.070]
        
        20-alpha-Dihydroprogesterone [D06.472.334.851.687.750.074]
        
        Hydroxyprogesterones [D06.472.334.851.687.750.478]
        
        Pregnanediol [D06.472.334.851.687.750.739]

Progesterone Preferred

Progesterone, (17 alpha)-Isomer Narrower

Progesterone, (9 beta,10 alpha)-Isomer Narrower

Progesterone, (13 alpha,17 alpha)-(+-)-Isomer Narrower

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