MeSH Browser

MeSH Heading: Histone-Lysine N-Methyltransferase
Tree Number(s): D08.811.913.555.500.800.200.500
Unique ID: D011495
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011495
Scope Note: An enzyme that catalyzes the methylation of the epsilon-amino group of lysine residues in proteins to yield epsilon mono-, di-, and trimethyllysine.
Entry Term(s): Histone-Lysine Methyltransferase; Protein Lysine Methyltransferase; Protein Methylase III; Protein Methyltransferase III
Registry Numbers: EC 2.1.1.43
Related Numbers: 9055-08-7
CAS Type 1 Name: S-Adenosyl-L-methionine:histone-L-lysine N(6)-methyltransferase
Previous Indexing: Lysine (1966-1976); Methyltransferases (1971-1976); Proteins (1966-1976); specific protein (1966-1976)
Public MeSH Note: 1998; see HISTONE-LYSINE METHYLTRANSFERASE 1991-97; see METHYLTRANSFERASES 1977-90
History Note: 1998 (1977)
Date Established: 1991/01/01
Date of Entry: 1976/05/21
Revision Date: 2018/01/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0017870
Registry Numbers: EC 2.1.1.43
Related Numbers: 9055-08-7
Scope Note: An enzyme that catalyzes the methylation of the epsilon-amino group of lysine residues in proteins to yield epsilon mono-, di-, and trimethyllysine.
Terms: Histone-Lysine N-Methyltransferase Preferred Term
Term UI T033957
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1977); Protein Lysine Methyltransferase
Term UI T033953
Date05/30/1990
LexicalTag NON
ThesaurusID NLM (1991); Protein Methylase III
Term UI T033954
Date05/20/1976
LexicalTag NON
ThesaurusID UNK (19XX); Protein Methyltransferase III
Term UI T033955
Date05/20/1976
LexicalTag NON
ThesaurusID UNK (19XX); Histone-Lysine Methyltransferase
Term UI T033956
Date04/25/1997
LexicalTag NON
ThesaurusID NLM (1998)

Histone-Lysine N-Methyltransferase MeSH Descriptor Data 2024