MeSH Browser

MeSH Heading: Puromycin
Tree Number(s): D02.241.223.200.380; D03.633.100.759.590.138.711; D09.408.051.788; D13.570.583.138.711
Unique ID: D011691
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011691
Scope Note: A cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.
Entry Term(s): CL-13900; P-638; Puromycin Dihydrochloride; Puromycin Hydrochloride; Stylomycin
Pharm Action: Antimetabolites, Antineoplastic
Protein Synthesis Inhibitors
Trypanocidal Agents
Related Numbers: 53-79-2; 58-58-2; PGN54228S5
CAS Type 1 Name: Adenosine, 3'-((2-amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3'-deoxy-N,N-dimethyl-, (S)-
Public MeSH Note: 65
History Note: 65(63)
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Puromycin MeSH Descriptor Data 2025