MeSH Browser

MeSH Heading: RNA-Dependent RNA Polymerase
Tree Number(s): D08.811.913.696.445.735.780
Unique ID: D012324
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D012324
Scope Note: An enzyme that catalyses RNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time, and can initiate a chain de novo. (Enzyme Nomenclature, 1992, p293)
Entry Term(s): Nucleoside-Triphosphate:RNA Nucleotidyltransferase (RNA-directed); RNA Replicase; RNA-Dependent RNA Replicase; RNA-Directed RNA Polymerase
Previous Indexing: RNA Nucleotidyltransferases (1969-1974)
Public MeSH Note: 1991; see RNA NUCLEOTIDYLTRANSFERASES 1975-1990
History Note: 1991(1975)
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2020/06/22

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0019157
Scope Note: An enzyme that catalyses RNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time, and can initiate a chain de novo. (Enzyme Nomenclature, 1992, p293)
Terms: RNA-Dependent RNA Polymerase Preferred Term
Term UI T036599
Date11/14/1974
LexicalTag NON
ThesaurusID NLM (1975); RNA Replicase
Term UI T036598
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1975); Nucleoside-Triphosphate:RNA Nucleotidyltransferase (RNA-directed)
Term UI T001079624
Date04/30/2020
LexicalTag NON
ThesaurusID NLM (2021); RNA-Directed RNA Polymerase
Term UI T036600
Date02/06/1986
LexicalTag NON
ThesaurusID UNK (19XX); RNA-Dependent RNA Replicase
Term UI T001079626
Date04/30/2020
LexicalTag NON
ThesaurusID NLM (2021)

RNA-Dependent RNA Polymerase MeSH Descriptor Data 2025