MeSH Browser

MeSH Heading: Shwartzman Phenomenon
Tree Number(s): C14.907.454.810; C14.907.940.890; C15.378.463.515.810
Unique ID: D012790
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D012790
Scope Note: Hemorrhagic necrosis that was first demonstrated in rabbits with a two-step reaction, an initial local (intradermal) or general (intravenous) injection of a priming endotoxin (ENDOTOXINS) followed by a second intravenous endotoxin injection (provoking agent) 24 h later. The acute inflammation damages the small blood vessels. The following intravascular coagulation leads to capillary and venous THROMBOSIS and NECROSIS. Shwartzman phenomenon can also occur in other species with a single injection of a provoking agent, and during infections or pregnancy. Its susceptibility depends on the status of IMMUNE SYSTEM, coagulation, FIBRINOLYSIS, and blood flow.
Entry Term(s): Schwartzman Phenomenon; Schwartzman Reaction; Shwartzman Reaction
NLM Classification #: WH 312
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2010/06/25

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0019807
Scope Note: Hemorrhagic necrosis that was first demonstrated in rabbits with a two-step reaction, an initial local (intradermal) or general (intravenous) injection of a priming endotoxin (ENDOTOXINS) followed by a second intravenous endotoxin injection (provoking agent) 24 h later. The acute inflammation damages the small blood vessels. The following intravascular coagulation leads to capillary and venous THROMBOSIS and NECROSIS. Shwartzman phenomenon can also occur in other species with a single injection of a provoking agent, and during infections or pregnancy. Its susceptibility depends on the status of IMMUNE SYSTEM, coagulation, FIBRINOLYSIS, and blood flow.
Terms: Shwartzman Phenomenon Preferred Term
Term UI T037738
Date01/01/1999
LexicalTag EPO
ThesaurusID NLM (1966); Schwartzman Reaction
Term UI T694879
Date04/03/2007
LexicalTag NON
ThesaurusID NLM (2008); Shwartzman Reaction
Term UI T037739
Date12/22/1997
LexicalTag EPO
ThesaurusID NLM (1999); Schwartzman Phenomenon
Term UI T680365
Date08/28/2006
LexicalTag EPO
ThesaurusID NLM (2008)

Shwartzman Phenomenon MeSH Descriptor Data 2023