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Spasms, Infantile MeSH Descriptor Data 2023

MeSH Heading
Spasms, Infantile
Tree Number(s)
Unique ID
RDF Unique Identifier
epileptic seizures only: do not confuse with SPASM + INFANT for non-epileptic seizures in infants
Scope Note
An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)
Entry Term(s)
Cryptogenic Infantile Spasms
Cryptogenic West Syndrome
Infantile Spasms
Jackknife Seizures
Lightning Attacks
Nodding Spasm
Salaam Attacks
Salaam Seizures
Spasmus Nutans
Symptomatic Infantile Spasms
Symptomatic West Syndrome
West Syndrome
NLM Classification #
WS 430
Previous Indexing
Child, Preschool (1966-1976)
Convulsions (1966-1976)
Epilepsy (1966-1976)
Epilepsy, Petit Mal (1966-1976)
Infant (1966-1976)
Infant, Newborn (1966-1976)
Myoclonus (1966-1976)
Public MeSH Note
1977; see HYPSARRHYTHMIA 1963-76
History Note
Date Established
Date of Entry
Revision Date
Spasms, Infantile Preferred
Hypsarrhythmia Related
Jackknife Seizures Narrower
Symptomatic Infantile Spasms Narrower
Salaam Attacks Narrower
Spasmus Nutans Related
Cryptogenic Infantile Spasms Narrower
Nodding Spasm Narrower
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