MeSH Browser

MeSH Heading: Superoxides
Tree Number(s): D01.248.497.158.685.750.850; D01.339.431.374.850; D01.650.550.750.800; D02.389.593.374.850
Unique ID: D013481
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D013481
Scope Note: Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides.
Entry Term(s): Superoxide; Superoxide Anion; Superoxide Radical
Pharm Action: Oxidants
CAS Type 1 Name: Superoxide
NLM Classification #: QV 312
Previous Indexing: Anions (1974); Oxygen (1974)
See Also: Reactive Oxygen Species; Respiratory Burst; Superoxide Dismutase
Public MeSH Note: 1994; was SUPEROXIDE 1975-1993 (see under OXYGEN 1975-1983)
Online Note: use SUPEROXIDES to search SUPEROXIDE 1975-1993
History Note: 1994; was SUPEROXIDE 1975-1993 (see under OXYGEN 1975-1983)
Date Established: 1984/01/01
Date of Entry: 1974/11/11
Revision Date: 2023/02/26

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0020825
Scope Note: Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides.
Terms: Superoxides Preferred Term
Term UI T039546
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); Superoxide
Term UI T039545
Date07/02/1993
LexicalTag NON
ThesaurusID NLM (1994); Superoxide Anion
Term UI T039547
Date07/13/1981
LexicalTag NON
ThesaurusID UNK (19XX); Superoxide Radical
Term UI T039548
Date08/30/1982
LexicalTag NON
ThesaurusID UNK (19XX)

Superoxides MeSH Descriptor Data 2025