MeSH Browser

MeSH Heading: Theophylline
Tree Number(s): D03.132.960.751; D03.633.100.759.758.824.751
Unique ID: D013806
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D013806
Scope Note: A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
Entry Term(s): 1,3-Dimethylxanthine; 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione; Accurbron; Aerobin; Aerolate; Afonilum Retard; Aquaphyllin; Armophylline; Bronchoparat; Bronkodyl; Constant-T; Elixophyllin; Euphylong; Glycine Theophyllinate; Lodrane; Monospan; Nuelin; Nuelin S.A.; Quibron T-SR; Slo-Phyllin; Somophyllin-T; Sustaire; Synophylate; Theo Von Ct; Theo-24; Theo-Dur; Theobid; Theocin; Theoconfin Continuous; Theodur; Theolair; Theolix; Theon; Theonite; Theopek; Theophylline Anhydrous; Theophylline Sodium Glycinate; Theospan; Theostat; Theovent; Uniphyl; Uniphyllin; Uniphylline
Pharm Action: Bronchodilator Agents
Phosphodiesterase Inhibitors
Vasodilator Agents
Purinergic P1 Receptor Antagonists
Related Numbers: 0I55128JYK; 2S36N8T753; 58-55-9
CAS Type 1 Name: 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-
NLM Classification #: QV 107
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0021287
Related Numbers: 0I55128JYK; 2S36N8T753; 58-55-9
Scope Note: A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
Terms: Theophylline Preferred Term
Term UI T040538
Date01/01/1999
LexicalTag NON
ThesaurusID; 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
Term UI T040546
Date11/22/1996
LexicalTag NON
ThesaurusID NLM (1998); 1,3-Dimethylxanthine
Term UI T040519
Date07/30/1980
LexicalTag NON
ThesaurusID UNK (19XX)