MeSH Browser

MeSH Heading: Protein Engineering
Tree Number(s): E05.393.420.601
Unique ID: D015202
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015202
Scope Note: Procedures by which protein structure and function are changed or created in vitro by altering existing or synthesizing new structural genes that direct the synthesis of proteins with sought-after properties. Such procedures may include the design of MOLECULAR MODELS of proteins using COMPUTER GRAPHICS or other molecular modeling techniques; site-specific mutagenesis (MUTAGENESIS, SITE-SPECIFIC) of existing genes; and DIRECTED MOLECULAR EVOLUTION techniques to create new genes.
Entry Term(s): Genetic Engineering of Proteins; Genetic Engineering, Protein; Proteins, Genetic Engineering
NLM Classification #: QU 55.95
Previous Indexing: Genes, Structural (1983-1988); Genetic Intervention (1983-1988); Mutation (1983-1988)
See Also: Directed Molecular Evolution; Mutagenesis, Site-Directed
Public MeSH Note: 89
History Note: 89
Date Established: 1989/01/01
Date of Entry: 1988/04/30
Revision Date: 2004/07/30

Allowable Qualifiers: classification (CL)

economics (EC)

ethics (ES)

history (HI)

instrumentation (IS)

legislation & jurisprudence (LJ)

methods (MT)

standards (ST)

statistics & numerical data (SN)

trends (TD)

veterinary (VE)

Concept UI: M0023358
Scope Note: Procedures by which protein structure and function are changed or created in vitro by altering existing or synthesizing new structural genes that direct the synthesis of proteins with sought-after properties. Such procedures may include the design of MOLECULAR MODELS of proteins using COMPUTER GRAPHICS or other molecular modeling techniques; site-specific mutagenesis (MUTAGENESIS, SITE-SPECIFIC) of existing genes; and DIRECTED MOLECULAR EVOLUTION techniques to create new genes.
Terms: Protein Engineering Preferred Term
Term UI T044448
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1989); Genetic Engineering of Proteins
Term UI T044447
Date04/30/1988
LexicalTag NON
ThesaurusID UNK (19XX); Genetic Engineering, Protein
Term UI T044445
Date04/30/1988
LexicalTag NON
ThesaurusID UNK (19XX); Proteins, Genetic Engineering
Term UI T044446
Date04/30/1988
LexicalTag NON
ThesaurusID UNK (19XX)

Protein Engineering MeSH Descriptor Data 2025