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Oligonucleotide Probes MeSH Descriptor Data 2025


MeSH Heading
Oligonucleotide Probes
Tree Number(s)
D13.444.600.601
D27.505.259.750.600.650
D27.720.470.530.600.650
Unique ID
D015345
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015345
Scope Note
Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.
Entry Term(s)
Oligodeoxyribonucleotide Probes
Oligonucleotide Probe
Oligoribonucleotide Probes
Previous Indexing
Nucleic Acid Hybridization (1972-1988)
Oligonucleotides (1972-1988)
See Also
Nucleic Acid Hybridization
Oligonucleotide Array Sequence Analysis
Public MeSH Note
89
History Note
89
Date Established
1989/01/01
Date of Entry
1988/06/01
Revision Date
2020/06/17
Oligonucleotide Probes Preferred
Oligodeoxyribonucleotide Probes Narrower
Oligoribonucleotide Probes Narrower
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