MeSH Browser

MeSH Heading: Paraparesis, Tropical Spastic
Tree Number(s): C01.207.618.500; C01.925.782.815.200.470.710; C10.228.228.618.500; C10.228.854.525.700; C10.586.750.700
Unique ID: D015493
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015493
Scope Note: A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean, Colombia, India, and Africa, as well as in the southwestern region of Japan; associated with infection by HUMAN T-CELL LEUKEMIA VIRUS I. Clinical manifestations include a slowly progressive spastic weakness of the legs, increased reflexes, Babinski signs, incontinence, and loss of vibratory and position sensation. On pathologic examination inflammatory, demyelination, and necrotic lesions may be found in the spinal cord. (Adams et al., Principles of Neurology, 6th ed, p1239)
Entry Term(s): Familial Spastic Paraparesis, Htlv-1-Associated; HTLV I Associated Myelopathies; HTLV-I-Associated Myelopathy; HTLV-I-Associated Myelopathy-Tropical Spastic Paraparesis; Human T-Lymphotropic Virus Type 1 Associated Myelopathy; Myelopathies, HTLV I Associated; Myelopathy, Htlv-1-Associated; Myelopathy, Human T-Lymphotropic Virus Type 1 Associated; Paraplegia, Tropical Spastic; Tropical Spastic Paraparesis
Previous Indexing: HTLV Infections (1987-1988); Human T-Cell Leukemia Virus (1985-1988); Paralysis (1984-1988); Paraplegia (1983-1988); Retrovirus Infections (1985-1986)
Public MeSH Note: 1989
History Note: 1989
Date Established: 1989/01/01
Date of Entry: 1988/06/10
Revision Date: 2021/06/30

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

transmission (TM)

urine (UR)

veterinary (VE)

virology (VI)

Infections [C01]
- Central Nervous System Infections [C01.207]
  - Myelitis [C01.207.618]

Infections [C01]
- Virus Diseases [C01.925]
  - RNA Virus Infections [C01.925.782]
    - Retroviridae Infections [C01.925.782.815]
      - Deltaretrovirus Infections [C01.925.782.815.200]
        
        HTLV-I Infections [C01.925.782.815.200.470]
        
        Paraparesis, Tropical Spastic [C01.925.782.815.200.470.710]

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Central Nervous System Infections [C10.228.228]
    - Myelitis [C10.228.228.618]

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Spinal Cord Diseases [C10.228.854]
    - Myelitis [C10.228.854.525]

Nervous System Diseases [C10]
- Neuroinflammatory Diseases [C10.586]
  - Myelitis [C10.586.750]

Paraparesis, Tropical Spastic Preferred

Concept UI: M0023855
Scope Note: A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean, Colombia, India, and Africa, as well as in the southwestern region of Japan; associated with infection by HUMAN T-CELL LEUKEMIA VIRUS I. Clinical manifestations include a slowly progressive spastic weakness of the legs, increased reflexes, Babinski signs, incontinence, and loss of vibratory and position sensation. On pathologic examination inflammatory, demyelination, and necrotic lesions may be found in the spinal cord. (Adams et al., Principles of Neurology, 6th ed, p1239)
Terms: Paraparesis, Tropical Spastic Preferred Term
Term UI T045945
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1989); HTLV-I-Associated Myelopathy-Tropical Spastic Paraparesis
Term UI T369827
Date11/08/1999
LexicalTag NON
ThesaurusID NLM (2000); Myelopathy, Human T-Lymphotropic Virus Type 1 Associated
Term UI T369828
Date11/08/1999
LexicalTag NON
ThesaurusID NLM (2000); Paraplegia, Tropical Spastic
Term UI T369829
Date11/08/1999
LexicalTag NON
ThesaurusID NLM (2000); Familial Spastic Paraparesis, Htlv-1-Associated
Term UI T811813
Date11/15/2011
LexicalTag NON
ThesaurusID OMIM (2013); Human T-Lymphotropic Virus Type 1 Associated Myelopathy
Term UI T369826
Date11/08/1999
LexicalTag NON
ThesaurusID NLM (2000); HTLV I Associated Myelopathies
Term UI T045941
Date02/22/1989
LexicalTag NON
ThesaurusID NLM (1990); Myelopathies, HTLV I Associated
Term UI T045942
Date02/22/1989
LexicalTag NON
ThesaurusID NLM (1990); HTLV-I-Associated Myelopathy
Term UI T045943
Date12/08/1988
LexicalTag NON
ThesaurusID NLM (1990); Tropical Spastic Paraparesis
Term UI T045944
Date06/10/1988
LexicalTag NON
ThesaurusID UNK (19XX); Myelopathy, Htlv-1-Associated
Term UI T811814
Date11/15/2011
LexicalTag NON
ThesaurusID OMIM (2013)

Paraparesis, Tropical Spastic MeSH Descriptor Data 2025