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Lambert-Eaton Myasthenic Syndrome MeSH Descriptor Data 2021


MeSH Heading
Lambert-Eaton Myasthenic Syndrome
Tree Number(s)
C04.588.614.550.500.225
C04.730.856.490.225
C10.114.656.150
C10.574.781.588.225
C10.668.758.725.150
C20.111.258.500.150
Unique ID
D015624
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015624
Scope Note
An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)
Entry Term(s)
Eaton-Lambert Myasthenic Syndrome
Eaton-Lambert Syndrome
Lambert-Eaton Syndrome
Myasthenic Syndrome, Lambert-Eaton
Myasthenic-Myopathic Syndrome of Eaton-Lambert
Myasthenic-Myopathic Syndrome of Lambert-Eaton
Myopathic-Myasthenic Syndrome of Eaton-Lambert
Myopathic-Myasthenic Syndrome of Lambert-Eaton
Previous Indexing
Muscular Diseases (1967-1988)
Myasthenia Gravis (1980-1989)
Neuromuscular Diseases (1980-1989)
Neuromuscular Junction (1980-1986)
Public MeSH Note
1990
History Note
1990
Date Established
1990/01/01
Date of Entry
1989/04/07
Revision Date
2019/02/22
Lambert-Eaton Myasthenic Syndrome Preferred
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