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Myasthenia Gravis, Neonatal MeSH Descriptor Data 2023

MeSH Heading
Myasthenia Gravis, Neonatal
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Scope Note
A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually present at birth or develop in the first 3 days of life and consist of hypotonia and impaired respiratory, suck, and swallowing abilities. This condition is associated with the passive transfer of acetylcholine receptor antibodies through the placenta. In the majority of infants the myasthenic weakness resolves (i.e., transient neonatal myasthenia gravis) although this disorder may rarely continue beyond the neonatal period (i.e., persistent neonatal myasthenia gravis). (From Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology 1997 Jan;48(1):50-4)
Entry Term(s)
Antenatal Myasthenia Gravis
Myasthenia Gravis, Neonatal, Persistent
Myasthenia Gravis, Neonatal, Transient
Myasthenia Gravis, Persistent, Neonatal
Myasthenia Gravis, Transient, Neonatal
Neonatal Myasthenia Gravis
Neonatal Myasthenia Gravis, Persistent
Neonatal Myasthenia Gravis, Transient
Persistent Neonatal Myasthenia Gravis
Transient Neonatal Myasthenia Gravis
Previous Indexing
Myasthenia Gravis (1965-1999)
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Myasthenia Gravis, Neonatal Preferred
Myasthenia Gravis, Neonatal, Persistent Narrower
Antenatal Myasthenia Gravis Narrower
Myasthenia Gravis, Neonatal, Transient Narrower
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