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HIV Envelope Protein gp120 MeSH Descriptor Data 2021


MeSH Heading
HIV Envelope Protein gp120
Tree Number(s)
D12.776.964.775.325.164.249
D12.776.964.775.562.500.500
D12.776.964.970.880.325.164.249
D23.050.327.520.350
Unique ID
D015699
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015699
Scope Note
External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.
Entry Term(s)
Envelope Glycoprotein gp120, HIV
HIV Envelope Glycoprotein gp120
HTLV-III gp120
env Protein gp120, HIV
gp120 Envelope Glycoprotein, HIV
gp120(HIV)
Registry Number
0
NLM Classification #
WC 503
Previous Indexing
Retroviridae Proteins (1986-1989)
Viral Envelope Proteins (1983-1989)
See Also
Peptide T
Public MeSH Note
90
History Note
90
Date Established
1990/01/01
Date of Entry
1989/06/19
Revision Date
2007/07/09
HIV Envelope Protein gp120 Preferred
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