MeSH Browser

MeSH Heading: DNA, Antisense
Tree Number(s): D13.150.200; D13.444.308.150; D13.444.600.150.200; D27.720.470.530.600.150.200
Unique ID: D016373
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016373
Scope Note: DNA that is complementary to the sense strand. (The sense strand has the same sequence as the mRNA transcript. The antisense strand is the template for mRNA synthesis.) Synthetic antisense DNAs are used to hybridize to complementary sequences in target RNAs or DNAs to effect the functioning of specific genes for investigative or therapeutic purposes.
Entry Term(s): Anti-Sense DNA; Antisense DNA
Registry Number: 0
NLM Classification #: QU 58.5
Previous Indexing: DNA (1988-1990)
Public MeSH Note: 91
History Note: 91
Date Established: 1991/01/01
Date of Entry: 1990/05/25
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

DNA, Antisense MeSH Descriptor Data 2023