MeSH Browser

MeSH Heading: Oligonucleotides, Antisense
Tree Number(s): D13.150.480; D13.444.600.150.640; D13.695.578.424.480; D27.720.470.530.600.150.640
Unique ID: D016376
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016376
Annotation: coord IM with THIONUCLEOTIDES (IM or NIM if pertinent)
Scope Note: Short fragments of DNA or RNA that are used to alter the function of target RNAs or DNAs to which they hybridize.
Entry Term(s): Anti-Sense Oligonucleotide; Anti-Sense Oligonucleotides; Antisense Oligonucleotide; Antisense Oligonucleotides
NLM Classification #: QU 57
Previous Indexing: Oligonucleotides (1987-1990)
See Also: Morpholinos
Public MeSH Note: 91
History Note: 91
Date Established: 1991/01/01
Date of Entry: 1990/05/29
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0025055
Scope Note: Short fragments of DNA or RNA that are used to alter the function of target RNAs or DNAs to which they hybridize.
Terms: Oligonucleotides, Antisense Preferred Term
Term UI T048943
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1991); Anti-Sense Oligonucleotide
Term UI T000998062
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021); Antisense Oligonucleotide
Term UI T000996258
Date11/14/2019
LexicalTag NON
ThesaurusID NLM (2021); Anti-Sense Oligonucleotides
Term UI T048944
Date01/27/1993
LexicalTag NON
ThesaurusID NLM (1994); Antisense Oligonucleotides
Term UI T048942
Date04/26/1990
LexicalTag NON
ThesaurusID NLM (1991)

Oligonucleotides, Antisense MeSH Descriptor Data 2025