MeSH Browser

MeSH Heading: Morpholinos
Tree Number(s): D03.383.533.640.562; D13.695.578.424.337
Unique ID: D060172
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D060172
Scope Note: Synthetic analogs of NUCLEIC ACIDS composed of morpholine ring derivatives (MORPHOLINES) linked by phosphorodimidates. One standard DNA nucleic acid base (ADENINE; GUANINE; CYTOSINE; OR THYMINE) is bound to each morpholine ring.
Entry Term(s): MORF Oligomers; Morpholino; Morpholino Oligonucleotide; Morpholino Oligonucleotides; Morpholino Oligos; PMO Oligomers; Phosphorodiamidate Morpholino Oligomer; Phosphorodiamidate Morpholino Oligomers
See Also: Oligonucleotides, Antisense
Public MeSH Note: 2012; see MORPHOLINES 2003-2011
History Note: 2012
Date Established: 2012/01/01
Date of Entry: 2011/06/24
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0553190
Scope Note: Synthetic analogs of NUCLEIC ACIDS composed of morpholine ring derivatives (MORPHOLINES) linked by phosphorodimidates. One standard DNA nucleic acid base (ADENINE; GUANINE; CYTOSINE; OR THYMINE) is bound to each morpholine ring.
Terms: Morpholinos Preferred Term
Term UI T783286
Date01/03/2011
LexicalTag NON
ThesaurusID NLM (2012); Morpholino
Term UI T000996510
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); Morpholino Oligos
Term UI T783287
Date01/03/2011
LexicalTag NON
ThesaurusID NLM (2012); MORF Oligomers
Term UI T783383
Date01/04/2011
LexicalTag ACX
ThesaurusID NLM (2012); Morpholino Oligonucleotides
Term UI T783386
Date01/04/2011
LexicalTag NON
ThesaurusID NLM (2012); Phosphorodiamidate Morpholino Oligomer
Term UI T001008165
Date02/20/2020
LexicalTag NON
ThesaurusID NLM (2021); Phosphorodiamidate Morpholino Oligomers
Term UI T783384
Date01/04/2011
LexicalTag NON
ThesaurusID NLM (2012); Morpholino Oligonucleotide
Term UI T001008164
Date02/20/2020
LexicalTag NON
ThesaurusID NLM (2021); PMO Oligomers
Term UI T783385
Date01/04/2011
LexicalTag ACX
ThesaurusID NLM (2012)

Morpholinos MeSH Descriptor Data 2025