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Negative Staining MeSH Descriptor Data 2022


MeSH Heading
Negative Staining
Tree Number(s)
E01.370.225.500.620.670.520
E01.370.225.750.600.670.520
E05.200.500.620.670.520
E05.200.750.600.670.520
Unique ID
D016624
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016624
Scope Note
The technique of washing tissue specimens with a concentrated solution of a heavy metal salt and letting it dry. The specimen will be covered with a very thin layer of the metal salt, being excluded in areas where an adsorbed macromolecule is present. The macromolecules allow electrons from the beam of an electron microscope to pass much more readily than the heavy metal; thus, a reversed or negative image of the molecule is created.
Previous Indexing
Staining (1966-1991)
Public MeSH Note
92
History Note
92
Date Established
1992/01/01
Date of Entry
1991/01/25
Revision Date
2011/06/24
Negative Staining Preferred
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