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Leuprolide
MeSH Descriptor Data 2025
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Leuprolide
Tree Number(s)
D06.472.699.327.740.320.400
D12.644.400.400.740.320.400
D12.644.456.460.480
D12.644.548.365.740.320.400
D12.776.631.650.405.740.320.400
Unique ID
D016729
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016729
Scope Note
A potent synthetic long-acting agonist of
GONADOTROPIN-RELEASING HORMONE
that regulates the synthesis and release of pituitary gonadotropins,
LUTEINIZING HORMONE
and
FOLLICLE STIMULATING HORMONE
.
Entry Term(s)
A-43818
Enantone
Leuprolide Acetate
Leuprolide Monoacetate
Leuprolide, (DL-Leu)-Isomer
Leuprolide, (L-Leu)-Isomer
Leuprorelin
Lupron
TAP-144
Pharm Action
Fertility Agents, Female
Antineoplastic Agents, Hormonal
Related Numbers
37JNS02E7V
53714-56-0
54785-87-4
61911-90-8
74381-53-6
88793-81-1
CAS Type 1 Name
Luteinizing hormone-releasing factor (pig), 6-D-leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-
Previous Indexing
Antineoplastic Agents (1984-1991)
Gonadorelin/analogs & derivatives (1980-1991)
Public MeSH Note
92; LEUPROLIDE was indexed under PEPTIDES 1975-76 & GONADORELIN/analogs & derivatives 1977-91
Online Note
use LEUPROLIDE (NM) to search LEUPROLIDE 1980-91
History Note
92; was LEUPROLIDE (NM) 1975-91
Date Established
1992/01/01
Date of Entry
1991/05/30
Revision Date
2015/11/24
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
agonists (AG)
analogs & derivatives (AA)
analysis (AN)
antagonists & inhibitors (AI)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
economics (EC)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
urine (UR)
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Peptide Hormones [D06.472.699]
Hypothalamic Hormones [D06.472.699.327]
Pituitary Hormone-Releasing Hormones [D06.472.699.327.740]
Gonadotropin-Releasing Hormone [D06.472.699.327.740.320]
Buserelin [D06.472.699.327.740.320.100]
Goserelin [D06.472.699.327.740.320.340]
Leuprolide [D06.472.699.327.740.320.400]
Nafarelin [D06.472.699.327.740.320.580]
Triptorelin Pamoate [D06.472.699.327.740.320.790]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Neuropeptides [D12.644.400]
Hypothalamic Hormones [D12.644.400.400]
Pituitary Hormone-Releasing Hormones [D12.644.400.400.740]
Gonadotropin-Releasing Hormone [D12.644.400.400.740.320]
Buserelin [D12.644.400.400.740.320.100]
Goserelin [D12.644.400.400.740.320.340]
Leuprolide [D12.644.400.400.740.320.400]
Nafarelin [D12.644.400.400.740.320.580]
Triptorelin Pamoate [D12.644.400.400.740.320.790]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Oligopeptides [D12.644.456]
Gonadotropin-Releasing Hormone [D12.644.456.460]
Buserelin [D12.644.456.460.150]
Goserelin [D12.644.456.460.315]
Leuprolide [D12.644.456.460.480]
Nafarelin [D12.644.456.460.600]
Triptorelin Pamoate [D12.644.456.460.800]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Peptide Hormones [D12.644.548]
Hypothalamic Hormones [D12.644.548.365]
Pituitary Hormone-Releasing Hormones [D12.644.548.365.740]
Gonadotropin-Releasing Hormone [D12.644.548.365.740.320]
Buserelin [D12.644.548.365.740.320.100]
Goserelin [D12.644.548.365.740.320.340]
Leuprolide [D12.644.548.365.740.320.400]
Nafarelin [D12.644.548.365.740.320.580]
Triptorelin Pamoate [D12.644.548.365.740.320.790]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Nerve Tissue Proteins [D12.776.631]
Neuropeptides [D12.776.631.650]
Hypothalamic Hormones [D12.776.631.650.405]
Pituitary Hormone-Releasing Hormones [D12.776.631.650.405.740]
Gonadotropin-Releasing Hormone [D12.776.631.650.405.740.320]
Buserelin [D12.776.631.650.405.740.320.100]
Goserelin [D12.776.631.650.405.740.320.340]
Leuprolide [D12.776.631.650.405.740.320.400]
Nafarelin [D12.776.631.650.405.740.320.580]
Triptorelin Pamoate [D12.776.631.650.405.740.320.790]
Expand All
Collapse All
Leuprolide
Preferred
Concept UI
M0025473
Related Numbers
37JNS02E7V
53714-56-0
54785-87-4
61911-90-8
74381-53-6
88793-81-1
Scope Note
A potent synthetic long-acting agonist of
GONADOTROPIN-RELEASING HORMONE
that regulates the synthesis and release of pituitary gonadotropins,
LUTEINIZING HORMONE
and
FOLLICLE STIMULATING HORMONE
.
Terms
Leuprolide
Preferred Term
Term UI
T050140
Date
01/01/1999
LexicalTag
NON
ThesaurusID
Leuprorelin
Term UI
T050141
Date
01/03/1991
LexicalTag
NON
ThesaurusID
TAP-144
Narrower
Concept UI
M0025474
Terms
TAP-144
Preferred Term
Term UI
T050145
Date
01/03/1991
LexicalTag
LAB
ThesaurusID
NLM (1992)
Enantone
Narrower
Concept UI
M0025475
Terms
Enantone
Preferred Term
Term UI
T050146
Date
11/13/1996
LexicalTag
TRD
ThesaurusID
NLM (1998)
Leuprolide, (L-Leu)-Isomer
Narrower
Concept UI
M0329428
Terms
Leuprolide, (L-Leu)-Isomer
Preferred Term
Term UI
T359622
Date
09/13/1999
LexicalTag
NON
ThesaurusID
NLM (1999)
Leuprolide, (DL-Leu)-Isomer
Narrower
Concept UI
M0329429
Terms
Leuprolide, (DL-Leu)-Isomer
Preferred Term
Term UI
T359623
Date
09/13/1999
LexicalTag
NON
ThesaurusID
NLM (1999)
Leuprolide Monoacetate
Narrower
Concept UI
M0329430
Terms
Leuprolide Monoacetate
Preferred Term
Term UI
T359624
Date
09/13/1999
LexicalTag
NON
ThesaurusID
NLM (1999)
Leuprolide Acetate
Narrower
Concept UI
M0329431
Terms
Leuprolide Acetate
Preferred Term
Term UI
T359625
Date
09/13/1999
LexicalTag
NON
ThesaurusID
Lupron
Narrower
Concept UI
M0369306
Terms
Lupron
Preferred Term
Term UI
T423767
Date
09/12/2000
LexicalTag
TRD
ThesaurusID
NLM (2002)
A-43818
Narrower
Concept UI
M0369307
Terms
A-43818
Preferred Term
Term UI
T423768
Date
09/12/2000
LexicalTag
LAB
ThesaurusID
NLM (2002)
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