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Antibodies, Bispecific MeSH Descriptor Data 2023


MeSH Heading
Antibodies, Bispecific
Tree Number(s)
D12.776.124.486.485.114.125
D12.776.124.790.651.114.134
D12.776.377.715.548.114.134
Unique ID
D018033
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018033
Annotation
do not coordinate with ANTIBODY FORMATION for /‌biosynthesis
Scope Note
Antibodies, often monoclonal, in which the two antigen-binding sites are specific for separate ANTIGENIC DETERMINANTS. They are artificial antibodies produced by chemical crosslinking, fusion of HYBRIDOMA cells, or by molecular genetic techniques. They function as the main mediators of targeted cellular cytotoxicity and have been shown to be efficient in the targeting of drugs, toxins, radiolabeled haptens, and effector cells to diseased tissue, primarily tumors.
Entry Term(s)
Bifunctional Antibodies
Bispecific Antibodies
Bispecific Monoclonal Antibodies
Pharm Action
Immunologic Factors
Registry Number
0
Previous Indexing
Antibodies (1985-1993)
specific Antibodies (1985-1993)
See Also
Immunotoxins
Radioimmunotherapy
Public MeSH Note
94
History Note
94
Date Established
1994/01/01
Date of Entry
1993/06/04
Revision Date
2010/06/25
Antibodies, Bispecific Preferred
Bispecific Monoclonal Antibodies Narrower
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