MeSH Browser

MeSH Heading: Tuberculosis, Multidrug-Resistant
Tree Number(s): C01.150.252.410.040.552.846.775
Unique ID: D018088
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018088
Annotation: coordinate with specific type of tuberculosis + specific antitubercular agents if pertinent; EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS is also available
Scope Note: Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS.
Entry Term(s): Tuberculosis, Drug-Resistant; Tuberculosis, MDR; Tuberculosis, Multi-Drug Resistant
Previous Indexing: Drug Resistance, Microbial (1990-1993); Tuberculosis (1990-1993); Tuberculosis, Pulmonary (1990-1993)
See Also: Drug Resistance, Multiple, Bacterial
Public MeSH Note: 94
History Note: 94
Date Established: 1994/01/01
Date of Entry: 1993/06/03
Revision Date: 2019/06/17

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

transmission (TM)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0027284
Scope Note: Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS.
Terms: Tuberculosis, Multidrug-Resistant Preferred Term
Term UI T054124
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1994); Tuberculosis, MDR
Term UI T054123
Date02/25/1993
LexicalTag NON
ThesaurusID NLM (1994); Tuberculosis, Multi-Drug Resistant
Term UI T054125
Date02/25/1993
LexicalTag NON
ThesaurusID NLM (1994)

Tuberculosis, Multidrug-Resistant MeSH Descriptor Data 2025