MeSH Browser

MeSH Heading: Mice, Inbred CFTR
Tree Number(s): B01.050.050.199.520.520.445; B01.050.150.900.649.313.992.635.505.500.400.445
Unique ID: D018181
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018181
Annotation: NIM with no qualifiers when experimental animal
Scope Note: A strain of mice widely studied as a model for cystic fibrosis. These mice are generated from embryonic stem cells in which the CFTR (cystic fibrosis transmembrane conductance regulator) gene is inactivated by gene targeting. As a result, all mice have one copy of this altered gene in all their tissues. Mice homozygous for the disrupted gene exhibit many features common to young cystic fibrosis patients, including failure to thrive, meconium ileus, and alteration of mucous and serous glands.
Entry Term(s): Mice, CFTR; Mouse, CFTR; Mouse, Inbred CFTR
Previous Indexing: Mice (1992-1993)
Public MeSH Note: 94
History Note: 94
Date Established: 1994/01/01
Date of Entry: 1993/06/03
Revision Date: 2020/09/02

Allowable Qualifiers: abnormalities (AB)

anatomy & histology (AH)

blood (BL)

cerebrospinal fluid (CF)

classification (CL)

embryology (EM)

genetics (GE)

growth & development (GD)

immunology (IM)

injuries (IN)

metabolism (ME)

microbiology (MI)

parasitology (PS)

physiology (PH)

psychology (PX)

surgery (SU)

urine (UR)

virology (VI)

Eukaryota [B01]
- Animals [B01.050]
  - Animal Population Groups [B01.050.050]
    - Animals, Laboratory [B01.050.050.199]
      - Animals, Inbred Strains [B01.050.050.199.520]
        
        Mice, Inbred Strains [B01.050.050.199.520.520]
        
        Mice, Hairless [B01.050.050.199.520.520.200]
        
        Mice, Inbred A [B01.050.050.199.520.520.300]
        
        Mice, Inbred AKR [B01.050.050.199.520.520.318]
        
        Mice, Inbred BALB C [B01.050.050.199.520.520.338]
        
        Mice, Inbred C3H [B01.050.050.199.520.520.388]
        
        Mice, Inbred C57BL [B01.050.050.199.520.520.420]
        
        Mice, Inbred CBA [B01.050.050.199.520.520.440]
        
        Mice, Inbred CFTR [B01.050.050.199.520.520.445]
        
        Mice, Inbred DBA [B01.050.050.199.520.520.500]
        
        Mice, Inbred ICR [B01.050.050.199.520.520.510]
        
        Mice, Inbred MRL lpr [B01.050.050.199.520.520.555]
        
        Mice, Inbred NOD [B01.050.050.199.520.520.565]
        
        Mice, Inbred NZB [B01.050.050.199.520.520.580]
        
        Mice, Inbred SENCAR [B01.050.050.199.520.520.600]

Eukaryota [B01]
- Animals [B01.050]
  - Chordata [B01.050.150]
    - Vertebrates [B01.050.150.900]
      - Mammals [B01.050.150.900.649]
        
        Eutheria [B01.050.150.900.649.313]
        
        Rodentia [B01.050.150.900.649.313.992]
        
        Muridae [B01.050.150.900.649.313.992.635]
        
        Murinae [B01.050.150.900.649.313.992.635.505]
        
        Mice [B01.050.150.900.649.313.992.635.505.500]
        
        Mice, Inbred Strains [B01.050.150.900.649.313.992.635.505.500.400]
        
        Collaborative Cross Mice [B01.050.150.900.649.313.992.635.505.500.400.013]
        
        Mice, 129 Strain [B01.050.150.900.649.313.992.635.505.500.400.025]
        
        Mice, Hairless [B01.050.150.900.649.313.992.635.505.500.400.200]
        
        Mice, Inbred A [B01.050.150.900.649.313.992.635.505.500.400.300]
        
        Mice, Inbred AKR [B01.050.150.900.649.313.992.635.505.500.400.318]
        
        Mice, Inbred BALB C [B01.050.150.900.649.313.992.635.505.500.400.338]
        
        Mice, Inbred C3H [B01.050.150.900.649.313.992.635.505.500.400.388]
        
        Mice, Inbred C57BL [B01.050.150.900.649.313.992.635.505.500.400.420]
        
        Mice, Inbred CBA [B01.050.150.900.649.313.992.635.505.500.400.440]
        
        Mice, Inbred CFTR [B01.050.150.900.649.313.992.635.505.500.400.445]
        
        Mice, Inbred DBA [B01.050.150.900.649.313.992.635.505.500.400.500]
        
        Mice, Inbred ICR [B01.050.150.900.649.313.992.635.505.500.400.510]
        
        Mice, Inbred MRL lpr [B01.050.150.900.649.313.992.635.505.500.400.555]
        
        Mice, Inbred NOD [B01.050.150.900.649.313.992.635.505.500.400.565]
        
        Mice, Inbred NZB [B01.050.150.900.649.313.992.635.505.500.400.580]
        
        Mice, Inbred SENCAR [B01.050.150.900.649.313.992.635.505.500.400.600]

Mice, Inbred CFTR Preferred

Concept UI: M0027408
Scope Note: A strain of mice widely studied as a model for cystic fibrosis. These mice are generated from embryonic stem cells in which the CFTR (cystic fibrosis transmembrane conductance regulator) gene is inactivated by gene targeting. As a result, all mice have one copy of this altered gene in all their tissues. Mice homozygous for the disrupted gene exhibit many features common to young cystic fibrosis patients, including failure to thrive, meconium ileus, and alteration of mucous and serous glands.
Terms: Mice, Inbred CFTR Preferred Term
Term UI T054424
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1994); Mice, CFTR
Term UI T054421
Date03/19/1993
LexicalTag NON
ThesaurusID NLM (1994); Mouse, CFTR
Term UI T054422
Date03/19/1993
LexicalTag NON
ThesaurusID NLM (1994); Mouse, Inbred CFTR
Term UI T054423
Date03/19/1993
LexicalTag NON
ThesaurusID NLM (1994)

Mice, Inbred CFTR MeSH Descriptor Data 2025