MeSH Browser

MeSH Heading: Mice, Inbred MRL lpr
Tree Number(s): B01.050.050.199.520.520.555; B01.050.150.900.649.313.992.635.505.500.400.555
Unique ID: D019463
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019463
Annotation: NIM with no qualifiers when experimental animal
Scope Note: A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome, which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also, the MRL/lpr is a useful model to study behavioral and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents.
Entry Term(s): Mice, MRL lpr; Mouse, Inbred MRL lpr; Mouse, MRL lpr
Previous Indexing: Mice (1981-1996)
Public MeSH Note: 97
History Note: 97
Date Established: 1997/01/01
Date of Entry: 1996/06/19
Revision Date: 2020/09/02

Allowable Qualifiers: abnormalities (AB)

anatomy & histology (AH)

blood (BL)

cerebrospinal fluid (CF)

classification (CL)

embryology (EM)

genetics (GE)

growth & development (GD)

immunology (IM)

injuries (IN)

metabolism (ME)

microbiology (MI)

parasitology (PS)

physiology (PH)

psychology (PX)

surgery (SU)

urine (UR)

virology (VI)

Eukaryota [B01]
- Animals [B01.050]
  - Animal Population Groups [B01.050.050]
    - Animals, Laboratory [B01.050.050.199]
      - Animals, Inbred Strains [B01.050.050.199.520]
        
        Mice, Inbred Strains [B01.050.050.199.520.520]
        
        Mice, Hairless [B01.050.050.199.520.520.200]
        
        Mice, Inbred A [B01.050.050.199.520.520.300]
        
        Mice, Inbred AKR [B01.050.050.199.520.520.318]
        
        Mice, Inbred BALB C [B01.050.050.199.520.520.338]
        
        Mice, Inbred C3H [B01.050.050.199.520.520.388]
        
        Mice, Inbred C57BL [B01.050.050.199.520.520.420]
        
        Mice, Inbred CBA [B01.050.050.199.520.520.440]
        
        Mice, Inbred CFTR [B01.050.050.199.520.520.445]
        
        Mice, Inbred DBA [B01.050.050.199.520.520.500]
        
        Mice, Inbred ICR [B01.050.050.199.520.520.510]
        
        Mice, Inbred MRL lpr [B01.050.050.199.520.520.555]
        
        Mice, Inbred NOD [B01.050.050.199.520.520.565]
        
        Mice, Inbred NZB [B01.050.050.199.520.520.580]
        
        Mice, Inbred SENCAR [B01.050.050.199.520.520.600]

Eukaryota [B01]
- Animals [B01.050]
  - Chordata [B01.050.150]
    - Vertebrates [B01.050.150.900]
      - Mammals [B01.050.150.900.649]
        
        Eutheria [B01.050.150.900.649.313]
        
        Rodentia [B01.050.150.900.649.313.992]
        
        Muridae [B01.050.150.900.649.313.992.635]
        
        Murinae [B01.050.150.900.649.313.992.635.505]
        
        Mice [B01.050.150.900.649.313.992.635.505.500]
        
        Mice, Inbred Strains [B01.050.150.900.649.313.992.635.505.500.400]
        
        Collaborative Cross Mice [B01.050.150.900.649.313.992.635.505.500.400.013]
        
        Mice, 129 Strain [B01.050.150.900.649.313.992.635.505.500.400.025]
        
        Mice, Hairless [B01.050.150.900.649.313.992.635.505.500.400.200]
        
        Mice, Inbred A [B01.050.150.900.649.313.992.635.505.500.400.300]
        
        Mice, Inbred AKR [B01.050.150.900.649.313.992.635.505.500.400.318]
        
        Mice, Inbred BALB C [B01.050.150.900.649.313.992.635.505.500.400.338]
        
        Mice, Inbred C3H [B01.050.150.900.649.313.992.635.505.500.400.388]
        
        Mice, Inbred C57BL [B01.050.150.900.649.313.992.635.505.500.400.420]
        
        Mice, Inbred CBA [B01.050.150.900.649.313.992.635.505.500.400.440]
        
        Mice, Inbred CFTR [B01.050.150.900.649.313.992.635.505.500.400.445]
        
        Mice, Inbred DBA [B01.050.150.900.649.313.992.635.505.500.400.500]
        
        Mice, Inbred ICR [B01.050.150.900.649.313.992.635.505.500.400.510]
        
        Mice, Inbred MRL lpr [B01.050.150.900.649.313.992.635.505.500.400.555]
        
        Mice, Inbred NOD [B01.050.150.900.649.313.992.635.505.500.400.565]
        
        Mice, Inbred NZB [B01.050.150.900.649.313.992.635.505.500.400.580]
        
        Mice, Inbred SENCAR [B01.050.150.900.649.313.992.635.505.500.400.600]

Mice, Inbred MRL lpr Preferred

Concept UI: M0028954
Scope Note: A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome, which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also, the MRL/lpr is a useful model to study behavioral and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents.
Terms: Mice, Inbred MRL lpr Preferred Term
Term UI T058017
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1997); Mouse, Inbred MRL lpr
Term UI T058016
Date03/14/1996
LexicalTag NON
ThesaurusID NLM (1997); Mice, MRL lpr
Term UI T058018
Date03/14/1996
LexicalTag NON
ThesaurusID NLM (1997); Mouse, MRL lpr
Term UI T058019
Date03/14/1996
LexicalTag NON
ThesaurusID NLM (1997)

Mice, Inbred MRL lpr MeSH Descriptor Data 2025