NLM Logo

Mice, Inbred MRL lpr MeSH Descriptor Data 2023


MeSH Heading
Mice, Inbred MRL lpr
Tree Number(s)
B01.050.050.199.520.520.555
B01.050.150.900.649.313.992.635.505.500.400.555
Unique ID
D019463
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019463
Annotation
NIM with no qualifiers when experimental animal
Scope Note
A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome, which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also, the MRL/lpr is a useful model to study behavioral and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents.
Entry Term(s)
Mice, MRL lpr
Mouse, Inbred MRL lpr
Mouse, MRL lpr
Previous Indexing
Mice (1981-1996)
Public MeSH Note
97
History Note
97
Date Established
1997/01/01
Date of Entry
1996/06/19
Revision Date
2020/09/02
Mice, Inbred MRL lpr Preferred
page delivered in 0.168s