MeSH Browser

MeSH Heading: Receptors, Adrenergic, alpha-2
Tree Number(s): D12.776.543.750.670.300.300.300.200; D12.776.543.750.695.150.300.300.725; D12.776.543.750.720.330.300.300.200
Unique ID: D018341
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018341
Scope Note: A subclass of alpha-adrenergic receptors found on both presynaptic and postsynaptic membranes where they signal through Gi-Go G-PROTEINS. While postsynaptic alpha-2 receptors play a traditional role in mediating the effects of ADRENERGIC AGONISTS, the subset of alpha-2 receptors found on presynaptic membranes signal the feedback inhibition of NEUROTRANSMITTER release.
Entry Version: RECEPT ADREN ALPHA 2
Entry Term(s): Adrenergic Receptor alpha(2C); Adrenergic Receptor alpha(2d); Adrenergic Receptor alpha-2C; Adrenergic Receptor alpha-2b; Adrenergic Receptor, alpha-2; Adrenergic alpha-2 Receptors; Adrenergic alpha-2A Receptors; Adrenergic alpha-2B Receptors; Adrenergic alpha-2C Receptors; Adrenergic alpha-2D Receptors; Receptor, Adrenergic, alpha-2; Receptor, Adrenergic, alpha-2A; Receptor, Adrenergic, alpha-2B; Receptor, Adrenergic, alpha-2C; Receptor, Adrenergic, alpha-2D; Receptors, Adrenergic, alpha-2A; Receptors, Adrenergic, alpha-2B; Receptors, Adrenergic, alpha-2D; Receptors, alpha-2 Adrenergic; alpha 2 Adrenergic Receptors; alpha-2 Adrenergic Receptors; alpha-2A Adrenergic Receptor; alpha-2B Adrenergic Receptor; alpha-2C Adrenergic Receptor; alpha-2D Adrenergic Receptor
Previous Indexing: Receptors, Adrenergic, alpha (1977-1993)
Public MeSH Note: 1994; RECEPTORS, ADRENERGIC, ALPHA-2A was indexed under RECEPTORS, ADRENERGIC, ALPHA-2 1996-2010; ADRENERGIC RECEPTOR ALPHA-2B was indexed under RECEPTORS, ADRENERGIC, ALPHA-2 1997-2010; ADRENERGIC RECEPTOR ALPHA(2C) was indexed under RECEPTORS, ADRENERGIC, ALPHA-2 1995-2010; ADRENERGIC RECEPTOR ALPHA(2D) was indexed under RECEPTORS, ADRENERGIC, ALPHA-2 1997-2010
History Note: 1994
Entry Combination: agonists:Adrenergic alpha-2 Receptor Agonists; antagonists & inhibitors:Adrenergic alpha-2 Receptor Antagonists
Date Established: 1994/01/01
Date of Entry: 1993/06/21
Revision Date: 2016/06/17

Entry Combination: agonists:Adrenergic alpha-2 Receptor Agonists; antagonists & inhibitors:Adrenergic alpha-2 Receptor Antagonists
Allowable Qualifiers: administration & dosage (AD)

analysis (AN)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Biogenic Amine [D12.776.543.750.670]
        
        Receptors, Catecholamine [D12.776.543.750.670.300]
        
        Receptors, Adrenergic [D12.776.543.750.670.300.300]
        
        Receptors, Adrenergic, alpha [D12.776.543.750.670.300.300.300]
        
        Receptors, Adrenergic, alpha-1 [D12.776.543.750.670.300.300.300.100]
        
        Receptors, Adrenergic, alpha-2 [D12.776.543.750.670.300.300.300.200]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, G-Protein-Coupled [D12.776.543.750.695]
        
        Receptors, Catecholamine [D12.776.543.750.695.150]
        
        Receptors, Adrenergic [D12.776.543.750.695.150.300]
        
        Receptors, Adrenergic, alpha [D12.776.543.750.695.150.300.300]
        
        Receptors, Adrenergic, alpha-1 [D12.776.543.750.695.150.300.300.700]
        
        Receptors, Adrenergic, alpha-2 [D12.776.543.750.695.150.300.300.725]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Neurotransmitter [D12.776.543.750.720]
        
        Receptors, Catecholamine [D12.776.543.750.720.330]
        
        Receptors, Adrenergic [D12.776.543.750.720.330.300]
        
        Receptors, Adrenergic, alpha [D12.776.543.750.720.330.300.300]
        
        Receptors, Adrenergic, alpha-1 [D12.776.543.750.720.330.300.300.100]
        
        Receptors, Adrenergic, alpha-2 [D12.776.543.750.720.330.300.300.200]

Receptors, Adrenergic, alpha-2 Preferred

Concept UI: M0027575
Scope Note: A subclass of alpha-adrenergic receptors found on both presynaptic and postsynaptic membranes where they signal through Gi-Go G-PROTEINS. While postsynaptic alpha-2 receptors play a traditional role in mediating the effects of ADRENERGIC AGONISTS, the subset of alpha-2 receptors found on presynaptic membranes signal the feedback inhibition of NEUROTRANSMITTER release.
Terms: Receptors, Adrenergic, alpha-2 Preferred Term
Term UI T054718
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1994); alpha 2 Adrenergic Receptors
Term UI T054713
Date04/16/1993
LexicalTag NON
ThesaurusID NLM (1994); Receptor, Adrenergic, alpha-2
Term UI T054714
Date04/16/1993
LexicalTag NON
ThesaurusID NLM (1994); Adrenergic Receptor, alpha-2
Term UI T054712
Date04/16/1993
LexicalTag NON
ThesaurusID NLM (1994); Adrenergic alpha-2 Receptors
Term UI T054716
Date04/14/1993
LexicalTag NON
ThesaurusID NLM (1994); Receptors, alpha-2 Adrenergic
Term UI T054717
Date04/16/1993
LexicalTag NON
ThesaurusID NLM (1994); alpha-2 Adrenergic Receptors
Term UI T054715
Date04/16/1993
LexicalTag NON
ThesaurusID NLM (1994)

Receptor, Adrenergic, alpha-2C Narrower

Receptor, Adrenergic, alpha-2A Narrower

Receptor, Adrenergic, alpha-2B Narrower

Receptor, Adrenergic, alpha-2D Narrower

Receptors, Adrenergic, alpha-2 MeSH Descriptor Data 2025