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PrPC Proteins MeSH Descriptor Data 2022


MeSH Heading
PrPC Proteins
Tree Number(s)
D12.776.785.340.500
Unique ID
D018621
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018621
Annotation
PrPC stands for PRion Protein Cellular; do not confuse with PRPSC PROTEINS which are scrapie prion proteins
Scope Note
Normal cellular isoform of PRION PROTEINS encoded by a chromosomal gene and found in normal and scrapie-infected brain tissue, and other normal tissue. PrPC are protease-sensitive proteins whose function is unknown. Posttranslational modification of PrPC into PrPSC leads to infectivity.
Entry Version
PRPC
Entry Term(s)
Cp 33-35
Cp33-35, Scrapie
PrP-sen
Scrapie Amyloid Precursor Protein
Registry Number
0
Previous Indexing
Prions (1992-1994)
Public MeSH Note
95; SCRAPIE AMYLOID PRECURSOR PROTEIN was indexed under PRIONS & PROTEIN PRECURSORS 1992-94 and under VIRAL PROTEINS 1989-91
Online Note
use PRPC PROTEINS (NM) to search SCRAPIE AMYLOID PRECURSOR PROTEIN 1989-94
History Note
95; SCRAPIE AMYLOID PRECURSOR PROTEIN was NM 1989-94
Date Established
1995/01/01
Date of Entry
1994/04/16
Revision Date
2016/06/13
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