MeSH Browser

MeSH Heading: Lamivudine
Tree Number(s): D03.383.742.680.245.500.950.500; D13.570.230.329.950.500; D13.570.230.500.925.500; D13.570.685.245.500.950.500
Unique ID: D019259
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019259
Scope Note: A reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.
Entry Term(s): 2',3'-Dideoxy-3'-thiacytidine; 2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-cis)-; 3TC Lamivudine; BCH-189; Epivir; GR-109714X; GR109714X; Lamivudine, (+)-cis-; Lamivudine, (+-)-trans-; Lamivudine, (2S-cis)-Isomer
Pharm Action: Reverse Transcriptase Inhibitors
Anti-HIV Agents
Registry Numbers: 2T8Q726O95; 0; 134680-32-3; H6S9D88T3D; 77ANF82R6X
Related Numbers: 134678-17-4; 134680-32-3; 77ANF82R6X; H6S9D88T3D
Previous Indexing: Cytosine/analogs & derivatives (1991-1992); Zalcitabine/analogs & derivatives (1993-1996)
Public MeSH Note: 97; LAMIVUDINE was indexed under ZALCITABINE/analogs & derivatives 1993-96 and CYTOSINE/analogs & derivatives 1991-92
Online Note: use LAMIVUDINE (NM) to search LAMIVUDINE 1991-96
History Note: 97; was LAMIVUDINE (NM) 1991-96
Date Established: 1997/01/01
Date of Entry: 1996/06/10
Revision Date: 2021/10/18

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0028682
Registry Numbers: 2T8Q726O95
Related Numbers: 134678-17-4; 134680-32-3; 77ANF82R6X; H6S9D88T3D
Scope Note: A reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.
Terms: Lamivudine Preferred Term
Term UI T057379
Date01/01/1999
LexicalTag NON
ThesaurusID; 2',3'-Dideoxy-3'-thiacytidine
Term UI T057378
Date11/13/1995
LexicalTag NON
ThesaurusID NLM (1997); 2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-cis)-
Term UI T001110260
Date08/17/2021
LexicalTag NON
ThesaurusID NLM (2023); 3TC Lamivudine
Term UI T001111514
Date09/10/2021
LexicalTag NON
ThesaurusID NLM (2023)

Lamivudine MeSH Descriptor Data 2024