MeSH Browser

MeSH Heading: Glycyrrhizic Acid
Tree Number(s): D02.455.849.919.530.466
Unique ID: D019695
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019695
Annotation: do not confuse with GLYCYRRHETINIC ACID
Scope Note: A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.
Entry Term(s): Diammonium Glycyrrhizinate; Dipotassium Glycyrrhizinate; Glycyrrhizin; Glycyrrhizinic Acid; Zinc Glycyrrhizate
Pharm Action: Anti-Inflammatory Agents
Registry Number: 6FO62043WK
Related Numbers: 1405-86-3; CA2Y0FE3FX
CAS Type 1 Name: alpha-D-glucopyranosiduronic acid, (3 beta,20 beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-
Previous Indexing: Glycyrrhetinic Acid (1977-1997); Glycyrrhiza (1976-1985)
Public MeSH Note: 98; GLYCYRRHIZIC ACID was indexed under GLYCYRRHETINIC ACID 1979-97, GLYCYRRHIZA 1976-79, GLUCOSIDURONATES 1976-79, & ENOXOLONE 1977-79
History Note: 98; see GLYCYRRHIZIC ACID (NM) 1976-97
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Organic Chemicals [D02]
- Hydrocarbons [D02.455]
  - Terpenes [D02.455.849]
    - Triterpenes [D02.455.849.919]
      - Pentacyclic Triterpenes [D02.455.849.919.530]
        
        Escin [D02.455.849.919.530.333]
        
        Glycyrrhetinic Acid [D02.455.849.919.530.444]
        
        Glycyrrhizic Acid [D02.455.849.919.530.466]
        
        Lupanes [D02.455.849.919.530.600]
        
        Oleanolic Acid [D02.455.849.919.530.733]

Glycyrrhizic Acid Preferred

Concept UI: M0029245
Registry Number: 6FO62043WK
Related Numbers: 1405-86-3; CA2Y0FE3FX
Scope Note: A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.
Terms: Glycyrrhizic Acid Preferred Term
Term UI T058565
Date01/01/1999
LexicalTag NON
ThesaurusID; Glycyrrhizinic Acid
Term UI T058567
Date11/05/1996
LexicalTag NON
ThesaurusID; Glycyrrhizin
Term UI T058566
Date11/05/1996
LexicalTag NON
ThesaurusID

Zinc Glycyrrhizate Narrower

Diammonium Glycyrrhizinate Narrower

Dipotassium Glycyrrhizinate Narrower

Glycyrrhizic Acid MeSH Descriptor Data 2023