MeSH Browser

MeSH Heading: 11-beta-Hydroxysteroid Dehydrogenases
Tree Number(s): D08.811.682.047.436.174; D08.811.682.047.820.100
Unique ID: D042842
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D042842
Scope Note: Hydroxysteroid dehydrogenases that catalyzes the reversible conversion of CORTISOL to the inactive metabolite CORTISONE. Enzymes in this class can utilize either NAD or NADP as cofactors.
Entry Term(s): 11 beta-Hydroxysteroid Dehydrogenase; 11-Hydroxysteroid Dehydrogenase; 11B-Hydroxysteroid Dehydrogenase; 11beta-Hydroxysteroid Dehydrogenase; Corticosteroid 11-Oxidoreductase; Corticosteroid 11-Reductase; Cortisone 11-Oxoreductase
Related Numbers: 9041-46-7
Previous Indexing: Hydroxysteroid Dehydrogenases (1978-2003)
Public MeSH Note: 2004; 11BETA-HYDROXYSTEROID DEHYDROGENASE was indexed under HYDROXYSTEROID DEHYDROGENASES 1978-2003
History Note: 2004; use 11-BETA-HYDROXYSTEROID DEHYDROGENASES (NM) 1978-2003
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Oxidoreductases [D08.811.682]
    - Alcohol Oxidoreductases [D08.811.682.047]
      - Hydroxysteroid Dehydrogenases [D08.811.682.047.436]
        
        11-beta-Hydroxysteroid Dehydrogenases [D08.811.682.047.436.174]
        
        11-beta-Hydroxysteroid Dehydrogenase Type 1 [D08.811.682.047.436.174.300]
        
        11-beta-Hydroxysteroid Dehydrogenase Type 2 [D08.811.682.047.436.174.600]
        
        3-Hydroxysteroid Dehydrogenases [D08.811.682.047.436.350]
        
        17-Hydroxysteroid Dehydrogenases [D08.811.682.047.436.375]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Oxidoreductases [D08.811.682]
    - Alcohol Oxidoreductases [D08.811.682.047]
      - NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases [D08.811.682.047.820]
        
        11-beta-Hydroxysteroid Dehydrogenases [D08.811.682.047.820.100]
        
        11-beta-Hydroxysteroid Dehydrogenase Type 1 [D08.811.682.047.820.100.300]
        
        11-beta-Hydroxysteroid Dehydrogenase Type 2 [D08.811.682.047.820.100.600]
        
        20-Hydroxysteroid Dehydrogenases [D08.811.682.047.820.125]
        
        3-Hydroxyacyl CoA Dehydrogenases [D08.811.682.047.820.150]
        
        3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) [D08.811.682.047.820.186]
        
        3-Isopropylmalate Dehydrogenase [D08.811.682.047.820.193]
        
        3-Oxoacyl-(Acyl-Carrier-Protein) Reductase [D08.811.682.047.820.196]
        
        Acetoin Dehydrogenase [D08.811.682.047.820.200]
        
        Alcohol Dehydrogenase [D08.811.682.047.820.250]
        
        Aldo-Keto Reductases [D08.811.682.047.820.284]
        
        Carbonyl Reductase (NADPH) [D08.811.682.047.820.289]
        
        Glycerol-3-Phosphate Dehydrogenase (NAD+) [D08.811.682.047.820.293]
        
        Homoserine Dehydrogenase [D08.811.682.047.820.300]
        
        Hydroxybutyrate Dehydrogenase [D08.811.682.047.820.350]
        
        Hydroxyprostaglandin Dehydrogenases [D08.811.682.047.820.375]
        
        Hydroxypyruvate Reductase [D08.811.682.047.820.400]
        
        IMP Dehydrogenase [D08.811.682.047.820.450]
        
        Isocitrate Dehydrogenase [D08.811.682.047.820.475]
        
        Ketol-Acid Reductoisomerase [D08.811.682.047.820.487]
        
        L-Lactate Dehydrogenase [D08.811.682.047.820.493]
        
        Malate Dehydrogenase [D08.811.682.047.820.496]
        
        Malate Dehydrogenase (NADP+) [D08.811.682.047.820.498]
        
        Progesterone Reductase [D08.811.682.047.820.500]
        
        D-Xylulose Reductase [D08.811.682.047.820.800]
        
        Short Chain Dehydrogenase-Reductases [D08.811.682.047.820.900]

11-beta-Hydroxysteroid Dehydrogenases Preferred

Concept UI: M0076306
Related Numbers: 9041-46-7
Scope Note: Hydroxysteroid dehydrogenases that catalyzes the reversible conversion of CORTISOL to the inactive metabolite CORTISONE. Enzymes in this class can utilize either NAD or NADP as cofactors.
Terms: 11-beta-Hydroxysteroid Dehydrogenases Preferred Term
Term UI T540711
Date05/14/2003
LexicalTag NON
ThesaurusID NLM (2004); Cortisone 11-Oxoreductase
Term UI T106308
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); 11beta-Hydroxysteroid Dehydrogenase
Term UI T544166
Date06/23/2003
LexicalTag NON
ThesaurusID NLM (2004); 11-Hydroxysteroid Dehydrogenase
Term UI T106303
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); 11B-Hydroxysteroid Dehydrogenase
Term UI T527067
Date11/26/2002
LexicalTag NON
ThesaurusID NLM (2004); 11 beta-Hydroxysteroid Dehydrogenase
Term UI T106309
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Corticosteroid 11-Reductase
Term UI T106307
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Corticosteroid 11-Oxidoreductase
Term UI T106306
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004)

11-beta-Hydroxysteroid Dehydrogenases MeSH Descriptor Data 2025