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Aldo-Keto Reductases MeSH Descriptor Data 2021


MeSH Heading
Aldo-Keto Reductases
Tree Number(s)
D08.811.682.047.150.700.156
D08.811.682.047.820.284
Unique ID
D000074408
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000074408
Scope Note
A family of NADPH-dependent oxidoreductases that reduce carbonyl substrates including sugar-aldehydes, KETOSTEROIDS; keto-prostaglandins, and QUINONES. They are monomers of approximately 37 KDa and are characterized by a parallel beta-8 (BETA SHEET)-alpha 8 (ALPHA HELICES)-barrel structure that contains the NADP binding site. This conformation favors aromatic and apolar substrates.
Entry Term(s)
Aldo-Keto Reductase
Aldo-Keto Reductase Family
Aldo-Keto Reductase Superfamily
Registry Number
EC 1.1.1.-
Previous Indexing
Aldehyde Reductase (1976-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/04/06
Aldo-Keto Reductases Preferred
Aldo-Keto Reductase Narrower
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