- Concept UI
- M000626529
- Registry Numbers
- EC 1.1.1.357
- Scope Note
- Aldo-keto reductase that functions with 5-alpha and 5-beta-steroid reductases to convert steroid hormones into the 3-alpha or 5-alpha and 3-alpha or 5-beta-tetrahydrosteroid, including 5-ALPHA-DIHYDROTESTOSTERONE to ANDROSTANE-3,17-DIOL. It also binds to BILE ACIDS. Mutations in the AKR1C2 gene are associated with Type 8 DISORDER OF SEX DEVELOPMENT, 46,XY (SRXY8).
- Terms
-
Aldo-Keto Reductase Family 1 Member C2
Preferred Term
Term UI
T000915853
Date02/16/2017
LexicalTag
NON
ThesaurusID
NLM (2018)
-
Dihydrodiol Dehydrogenase 2
Term UI
T000915852
Date02/16/2017
LexicalTag
NON
ThesaurusID
NLM (2018)
-
AKR1C2 Protein
Term UI
T000915854
Date02/16/2017
LexicalTag
ABX
ThesaurusID
NLM (2018)
-
Dihydrodiol Dehydrogenase-Bile Acid Binding Protein
Term UI
T000915863
Date02/16/2017
LexicalTag
NON
ThesaurusID
NLM (2000)