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Aldo-Keto Reductase Family 1 Member C2 MeSH Descriptor Data 2023


MeSH Heading
Aldo-Keto Reductase Family 1 Member C2
Tree Number(s)
D08.811.682.047.150.700.156.750
D08.811.682.047.820.284.875
Unique ID
D000074422
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000074422
Scope Note
Aldo-keto reductase that functions with 5-alpha and 5-beta-steroid reductases to convert steroid hormones into the 3-alpha or 5-alpha and 3-alpha or 5-beta-tetrahydrosteroid, including 5-ALPHA-DIHYDROTESTOSTERONE to ANDROSTANE-3,17-DIOL. It also binds to BILE ACIDS. Mutations in the AKR1C2 gene are associated with Type 8 DISORDER OF SEX DEVELOPMENT, 46,XY (SRXY8).
Entry Term(s)
AKR1C2 Protein
Dihydrodiol Dehydrogenase 2
Dihydrodiol Dehydrogenase-Bile Acid Binding Protein
Registry Number
EC 1.1.1.357
Previous Indexing
Hydroxysteroid Dehydrogenases (2001-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2018/07/13
Aldo-Keto Reductase Family 1 Member C2 Preferred
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