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Aldo-Keto Reductase Family 1 Member C3 MeSH Descriptor Data 2023


MeSH Heading
Aldo-Keto Reductase Family 1 Member C3
Tree Number(s)
D08.811.682.047.150.700.156.875
D08.811.682.047.436.375.140
D08.811.682.047.820.284.937
D08.811.682.047.820.375.500
Unique ID
D000074425
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000074425
Scope Note
Aldo-keto reductase that functions as a bi-directional 17 BETA, 20 ALPHA-HYDROXYSTEROID DEHYDROGENASE. It catalyzes the reduction of PROSTAGLANDIN D2 and PROSTAGLANDIN H2, as well as the oxidation of 9alpha,11beta-PGF2 to prostaglandin D2. It can also interconvert estrogens, ANDROGENS; and PROGESTINS between their active forms and inactive metabolites.
Entry Term(s)
17-beta-Hydroxysteroid Dehydrogenase Type 5
AKR1C3 Protein
Dihydrodiol Dehydrogenase 3
Registry Number
EC 1.1.1.357
Previous Indexing
3-Hydroxysteroid Dehydrogenases (2004-2017)
Hydroxyprostaglandin Dehydrogenases (2004-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/04/05
Aldo-Keto Reductase Family 1 Member C3 Preferred
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