MeSH Browser

MeSH Heading: Short Chain Dehydrogenase-Reductases
Tree Number(s): D08.811.682.047.820.900
Unique ID: D000074583
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000074583
Scope Note: A large family of oxidoreductases that are predominantly NAD- or NADP-dependent and 250 to 350 amino acids in length. They generally consist of two PROTEIN DOMAINS: A catalytic N-terminal domain that binds the substrate, and a C-terminal coenzyme-binding domain.
Entry Term(s): Short Chain Dehydrogenase; Short Chain Dehydrogenase Family; Short Chain Dehydrogenase Superfamily; Short Chain Dehydrogenase-Reductase; Short Chain Dehydrogenases; Short-Chain Alcohol Dehydrogenase; Short-Chain Alcohol Dehydrogenases
Previous Indexing: Alcohol Dehydrogenase (1991-2017); Alcohol Oxidoreductases (1995-2017)
Public MeSH Note: 2018
History Note: 2018
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Oxidoreductases [D08.811.682]
    - Alcohol Oxidoreductases [D08.811.682.047]
      - NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases [D08.811.682.047.820]
        
        11-beta-Hydroxysteroid Dehydrogenases [D08.811.682.047.820.100]
        
        20-Hydroxysteroid Dehydrogenases [D08.811.682.047.820.125]
        
        3-Hydroxyacyl CoA Dehydrogenases [D08.811.682.047.820.150]
        
        3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) [D08.811.682.047.820.186]
        
        3-Isopropylmalate Dehydrogenase [D08.811.682.047.820.193]
        
        3-Oxoacyl-(Acyl-Carrier-Protein) Reductase [D08.811.682.047.820.196]
        
        Acetoin Dehydrogenase [D08.811.682.047.820.200]
        
        Alcohol Dehydrogenase [D08.811.682.047.820.250]
        
        Aldo-Keto Reductases [D08.811.682.047.820.284]
        
        Carbonyl Reductase (NADPH) [D08.811.682.047.820.289]
        
        Glycerol-3-Phosphate Dehydrogenase (NAD+) [D08.811.682.047.820.293]
        
        Homoserine Dehydrogenase [D08.811.682.047.820.300]
        
        Hydroxybutyrate Dehydrogenase [D08.811.682.047.820.350]
        
        Hydroxyprostaglandin Dehydrogenases [D08.811.682.047.820.375]
        
        Hydroxypyruvate Reductase [D08.811.682.047.820.400]
        
        IMP Dehydrogenase [D08.811.682.047.820.450]
        
        Isocitrate Dehydrogenase [D08.811.682.047.820.475]
        
        Ketol-Acid Reductoisomerase [D08.811.682.047.820.487]
        
        L-Lactate Dehydrogenase [D08.811.682.047.820.493]
        
        Malate Dehydrogenase [D08.811.682.047.820.496]
        
        Malate Dehydrogenase (NADP+) [D08.811.682.047.820.498]
        
        Progesterone Reductase [D08.811.682.047.820.500]
        
        D-Xylulose Reductase [D08.811.682.047.820.800]
        
        Short Chain Dehydrogenase-Reductases [D08.811.682.047.820.900]
        
        WW Domain-Containing Oxidoreductase [D08.811.682.047.820.900.500]

Short Chain Dehydrogenase-Reductases Preferred

Concept UI: M000627068
Scope Note: A large family of oxidoreductases that are predominantly NAD- or NADP-dependent and 250 to 350 amino acids in length. They generally consist of two PROTEIN DOMAINS: A catalytic N-terminal domain that binds the substrate, and a C-terminal coenzyme-binding domain.
Terms: Short Chain Dehydrogenase-Reductases Preferred Term
Term UI T000916558
Date03/01/2017
LexicalTag NON
ThesaurusID NLM (2018); Short Chain Dehydrogenases
Term UI T000916559
Date03/01/2017
LexicalTag NON
ThesaurusID NLM (2018); Short Chain Dehydrogenase Family
Term UI T000916560
Date03/01/2017
LexicalTag NON
ThesaurusID NLM (2018); Short-Chain Alcohol Dehydrogenases
Term UI T000916561
Date03/01/2017
LexicalTag NON
ThesaurusID NLM (2018); Short Chain Dehydrogenase Superfamily
Term UI T000916562
Date03/01/2017
LexicalTag NON
ThesaurusID NLM (2018); Short Chain Dehydrogenase
Term UI T000999135
Date11/22/2019
LexicalTag NON
ThesaurusID NLM (2021); Short-Chain Alcohol Dehydrogenase
Term UI T000999137
Date11/22/2019
LexicalTag NON
ThesaurusID NLM (2021); Short Chain Dehydrogenase-Reductase
Term UI T000999136
Date11/22/2019
LexicalTag NON
ThesaurusID NLM (2021)

Short Chain Dehydrogenase-Reductases MeSH Descriptor Data 2025