MeSH Browser

MeSH Heading: Progesterone Reductase
Tree Number(s): D08.811.682.047.436.350.700; D08.811.682.047.820.500
Unique ID: D011375
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011375
Scope Note: An enzyme that catalyzes the reduction of a 3 beta-hydroxy-delta(5)-steroid to 3-oxo-delta(4)-steroid in the presence of NAD. It converts pregnenolone to progesterone and dehydroepiandrosterone to androstenedione. EC 1.1.1.145.
Entry Term(s): 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase; 5-Ene-3 beta-hydroxysteroid Dehydrogenase; Steroid delta(5)-3 beta-ol Dehydrogenase
Registry Number: EC 1.1.1.145
CAS Type 1 Name: 3 beta-Hydroxy-delta(5)-steroid:NAD+ 3-oxidoreductase
Previous Indexing: Hydroxysteroid Dehydrogenases (1972-1974)
Public MeSH Note: 91; was see under 3-HYDROXYSTEROID DEHYDROGENASES 1975-90
History Note: 91(75); was see under 3-HYDROXYSTEROID DEHYDROGENASES 1975-90
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Oxidoreductases [D08.811.682]
    - Alcohol Oxidoreductases [D08.811.682.047]
      - Hydroxysteroid Dehydrogenases [D08.811.682.047.436]
        
        3-Hydroxysteroid Dehydrogenases [D08.811.682.047.436.350]
        
        3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) [D08.811.682.047.436.350.100]
        
        Cholesterol Oxidase [D08.811.682.047.436.350.150]
        
        Progesterone Reductase [D08.811.682.047.436.350.700]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Oxidoreductases [D08.811.682]
    - Alcohol Oxidoreductases [D08.811.682.047]
      - NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases [D08.811.682.047.820]
        
        11-beta-Hydroxysteroid Dehydrogenases [D08.811.682.047.820.100]
        
        20-Hydroxysteroid Dehydrogenases [D08.811.682.047.820.125]
        
        3-Hydroxyacyl CoA Dehydrogenases [D08.811.682.047.820.150]
        
        3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) [D08.811.682.047.820.186]
        
        3-Isopropylmalate Dehydrogenase [D08.811.682.047.820.193]
        
        3-Oxoacyl-(Acyl-Carrier-Protein) Reductase [D08.811.682.047.820.196]
        
        Acetoin Dehydrogenase [D08.811.682.047.820.200]
        
        Alcohol Dehydrogenase [D08.811.682.047.820.250]
        
        Aldo-Keto Reductases [D08.811.682.047.820.284]
        
        Carbonyl Reductase (NADPH) [D08.811.682.047.820.289]
        
        Glycerol-3-Phosphate Dehydrogenase (NAD+) [D08.811.682.047.820.293]
        
        Homoserine Dehydrogenase [D08.811.682.047.820.300]
        
        Hydroxybutyrate Dehydrogenase [D08.811.682.047.820.350]
        
        Hydroxyprostaglandin Dehydrogenases [D08.811.682.047.820.375]
        
        Hydroxypyruvate Reductase [D08.811.682.047.820.400]
        
        IMP Dehydrogenase [D08.811.682.047.820.450]
        
        Isocitrate Dehydrogenase [D08.811.682.047.820.475]
        
        Ketol-Acid Reductoisomerase [D08.811.682.047.820.487]
        
        L-Lactate Dehydrogenase [D08.811.682.047.820.493]
        
        Malate Dehydrogenase [D08.811.682.047.820.496]
        
        Malate Dehydrogenase (NADP+) [D08.811.682.047.820.498]
        
        Progesterone Reductase [D08.811.682.047.820.500]
        
        D-Xylulose Reductase [D08.811.682.047.820.800]
        
        Short Chain Dehydrogenase-Reductases [D08.811.682.047.820.900]

Progesterone Reductase Preferred

Concept UI: M0017673
Registry Number: EC 1.1.1.145
Scope Note: An enzyme that catalyzes the reduction of a 3 beta-hydroxy-delta(5)-steroid to 3-oxo-delta(4)-steroid in the presence of NAD. It converts pregnenolone to progesterone and dehydroepiandrosterone to androstenedione. EC 1.1.1.145.
Terms: Progesterone Reductase Preferred Term
Term UI T033554
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); 5-Ene-3 beta-hydroxysteroid Dehydrogenase
Term UI T033556
Date11/29/1982
LexicalTag NON
ThesaurusID UNK (19XX); 3 beta-Hydroxy-delta-5-Steroid Dehydrogenase
Term UI T033553
Date01/07/1977
LexicalTag NON
ThesaurusID UNK (19XX); Steroid delta(5)-3 beta-ol Dehydrogenase
Term UI T033555
Date04/23/1981
LexicalTag NON
ThesaurusID UNK (19XX)

Progesterone Reductase MeSH Descriptor Data 2023