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Ketol-Acid Reductoisomerase MeSH Descriptor Data 2026
An enzyme that catalyzes the oxidation of (R)-2,3-dihydroxy-3-methylbutanoate to (S)-2-hydroxy-2-methyl-3-oxobutanoate in the presence of NADP. It is involved in the biosynthesis of VALINE; LEUCINE; ISOLEUCINE; pentothenate and COENZYME A. This enzyme was formerly classified as EC 1.1.1.89.
Entry Term(s)
Acetohydroxy Acid Isomeroreductase
Alpha-Acetohydroxyacid Isomeroreductase
Dihydroxyisovalerate Dehydrogenase (Isomerizing)
Hydroxyacid Reductoisomerase
Isomeroreductase
Registry Numbers
EC 1.1.1.86
Related Numbers
9075-02-9
Public MeSH Note
2006; KETOL-ACID REDUCTOISOMERASE was indexed under ALCOHOL OXODOREDUCTASES 1983-2000, & under VALERATES 1970-1982
An enzyme that catalyzes the oxidation of (R)-2,3-dihydroxy-3-methylbutanoate to (S)-2-hydroxy-2-methyl-3-oxobutanoate in the presence of NADP. It is involved in the biosynthesis of VALINE; LEUCINE; ISOLEUCINE; pentothenate and COENZYME A. This enzyme was formerly classified as EC 1.1.1.89.