MeSH Browser

MeSH Heading: alpha-Methyltyrosine
Tree Number(s): D12.125.072.050.875.485.050
Unique ID: D019805
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019805
Scope Note: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)
Entry Term(s): DL-Tyrosine, alpha-methyl-; Demser; Metirosine; Metyrosine; Racemetirosine; Racemetyrosine; SM-88; alpha-MPT; alpha-Methyl-p-tyrosine; alpha-Methyl-para-tyrosine; alpha-Methyltyrosine Hydrochloride; alpha-Methyltyrosine, (+,-)-Isomer; alpha-Methyltyrosine, (D,L)-Isomer; alpha-Methyltyrosine, (L)-Isomer
Pharm Action: Enzyme Inhibitors
Registry Numbers: 658-48-0; 0; 30625-05-9; DOQ0J0TPF7; X88TTO174Z
Related Numbers: 620-30-4; 672-87-7
Previous Indexing: Methyltyrosines (1979-1997)
Public MeSH Note: 98; ALPHA-METHYLTYROSINE was indexed under METHYLTYROSINES 1979-97
History Note: 98; use ALPHA-METHYLTYROSINE (NM) 1979-97
Entry Combination: analogs & derivatives:Methyltyrosines
Date Introduced: 1998/01/01
Last Updated: 2026/01/01

Entry Combination: analogs & derivatives:Methyltyrosines
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0029394
Registry Numbers: 658-48-0
Related Numbers: 620-30-4; 672-87-7
Scope Note: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)
Terms: alpha-Methyltyrosine Preferred Term
Term UI T058919
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1998); alpha-Methyl-p-tyrosine
Term UI T058920
Date12/27/1996
LexicalTag NON
ThesaurusID NLM (1998); alpha-Methyl-para-tyrosine
Term UI T058921
Date12/27/1996
LexicalTag NON
ThesaurusID NLM (1998); alpha-MPT
Term UI T058924
Date12/27/1996
LexicalTag NON
ThesaurusID NLM (1998)

Concept UI: M0373730
Registry Numbers: X88TTO174Z
Terms: Racemetirosine Preferred Term
Term UI T429968
Date11/30/2000
LexicalTag NON
ThesaurusID; alpha-Methyltyrosine, (+,-)-Isomer
Term UI T429971
Date11/30/2000
LexicalTag NON
ThesaurusID NLM (2002); alpha-Methyltyrosine, (D,L)-Isomer
Term UI T429970
Date11/30/2000
LexicalTag NON
ThesaurusID NLM (2002); DL-Tyrosine, alpha-methyl-
Term UI T429969
Date11/30/2000
LexicalTag NON
ThesaurusID NLM (2002); Racemetyrosine
Term UI T001147048
Date02/11/2025
LexicalTag NON
ThesaurusID NLM (2022)

alpha-Methyltyrosine MeSH Descriptor Data 2026