MeSH Browser

MeSH Heading: Nuclear Localization Signals
Tree Number(s): D12.644.770.610; G02.111.570.060.670.610
Unique ID: D019913
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019913
Scope Note: Short, predominantly basic amino acid sequences identified as nuclear import signals for some proteins. These sequences are believed to interact with specific receptors at the NUCLEAR PORE.
Entry Term(s): NLS Peptide; Nuclear Localization Signal; Nuclear Localization Signal Peptide
Registry Number: 0
See Also: Active Transport, Cell Nucleus
Public MeSH Note: 1998; NUCLEAR LOCALIZATION SIGNAL PEPTIDE was indexed under NUCLEAR PROTEINS 1990-2000
History Note: 1998; for NUCLEAR LOCALIZATION SIGNAL PEPTIDE use NUCLEAR LOCALIZATION SIGNAL (NM) 1990-2000
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2008/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0029588
Registry Number: 0
Scope Note: Short, predominantly basic amino acid sequences identified as nuclear import signals for some proteins. These sequences are believed to interact with specific receptors at the NUCLEAR PORE.
Terms: Nuclear Localization Signals Preferred Term
Term UI T617348
Date11/05/2004
LexicalTag NON
ThesaurusID NLM (2006); Nuclear Localization Signal Peptide
Term UI T201972
LexicalTag NON
ThesaurusID NLM (2001); Nuclear Localization Signal
Term UI T059333
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1998); NLS Peptide
Term UI T201971
LexicalTag ACX
ThesaurusID NLM (2001)

Nuclear Localization Signals MeSH Descriptor Data 2023