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Comet Assay MeSH Descriptor Data 2022


MeSH Heading
Comet Assay
Tree Number(s)
E05.196.401.153.150
E05.301.300.100.150
E05.393.560.150
E05.940.560.150
Unique ID
D020552
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020552
Scope Note
A genotoxicological technique for measuring DNA damage in an individual cell using single-cell gel electrophoresis. Cell DNA fragments assume a "comet with tail" formation on electrophoresis and are detected with an image analysis system. Alkaline assay conditions facilitate sensitive detection of single-strand damage.
Entry Term(s)
Alkaline Comet Assay
Alkaline Single-Cell Gel Electrophoresis Assay
Electrophoresis, Gel, Single-Cell
Gel Electrophoresis, Single-Cell
Previous Indexing
Electrophoresis (1990-1999)
Electrophoresis, Agar Gel (1990-1999)
Mutagenicity Tests (1992-1999)
See Also
DNA Damage
Public MeSH Note
2000
History Note
2000
Date Established
2000/01/01
Date of Entry
1999/11/03
Revision Date
2008/07/08
Comet Assay Preferred
Alkaline Comet Assay Narrower
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