MeSH Browser

MeSH Heading: Peptide Elongation Factor 1
Tree Number(s): D08.811.277.040.330.300.100.101; D12.776.157.325.150.101; D12.776.476.338.100.101; D12.776.835.700.350.101
Unique ID: D020648
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020648
Scope Note: Peptide elongation factor 1 is a multisubunit protein that is responsible for the GTP-dependent binding of aminoacyl-tRNAs to eukaryotic ribosomes. The alpha subunit (EF-1alpha) binds aminoacyl-tRNA and transfers it to the ribosome in a process linked to GTP hydrolysis. The beta and delta subunits (EF-1beta, EF-1delta) are involved in exchanging GDP for GTP. The gamma subunit (EF-1gamma) is a structural component.
Entry Term(s): EF 1; EF-1; EF-1H; EF-1alpha; EF-1beta; EF-1delta; EF-1gamma; Elongation Factor 1; Elongation Factor 1alpha; Elongation Factor 1beta; Elongation Factor 1delta; Elongation Factor 1gamma
Previous Indexing: Peptide Elongation Factors (1973-1999)
Public MeSH Note: 2000; ELONGATION FACTOR 1 was indexed under PEPTIDE ELONGATION FACTORS 1980-1999; ELONGATION FACTOR 1GAMMA was indexed under PEPTIDE ELONGATION FACTORS 1994-1999
History Note: 2000; for ELONGATION FACTOR 1 use PEPTIDE ELONGATION FACTOR 1 (NM) 1980-1999; for ELONGATION FACTOR 1GAMMA use PEPTIDE ELONGATION FACTOR 1 (NM) 1994-1999
Date Established: 2000/01/01
Date of Entry: 1999/11/04
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0328220
Scope Note: Peptide elongation factor 1 is a multisubunit protein that is responsible for the GTP-dependent binding of aminoacyl-tRNAs to eukaryotic ribosomes. The alpha subunit (EF-1alpha) binds aminoacyl-tRNA and transfers it to the ribosome in a process linked to GTP hydrolysis. The beta and delta subunits (EF-1beta, EF-1delta) are involved in exchanging GDP for GTP. The gamma subunit (EF-1gamma) is a structural component.
Terms: Peptide Elongation Factor 1 Preferred Term
Term UI T358220
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); EF-1
Term UI T118223
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Elongation Factor 1
Term UI T118241
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); EF 1
Term UI T361786
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); EF-1H
Term UI T361787
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000)

Peptide Elongation Factor 1 MeSH Descriptor Data 2025