Denys-Drash Syndrome MeSH Descriptor Data 2025

MeSH Heading: Denys-Drash Syndrome
Tree Number(s): C04.557.435.595.220; C04.588.945.947.535.585.220; C04.700.900.220; C12.050.351.875.253.096.562; C12.050.351.937.820.535.585.220; C12.050.351.968.419.473.585.220; C12.200.706.316.096.562; C12.200.758.820.750.585.220; C12.200.777.419.473.585.220; C12.800.316.096.562; C12.900.820.535.585.220; C12.950.419.473.585.220; C12.950.983.535.585.220; C16.131.939.316.096.562; C16.320.700.900.220; C19.391.119.096.562
Unique ID: D030321
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D030321
Scope Note: A disorder of sex development characterized by UROGENITAL ABNORMALITIES; GONADAL DYSGENESIS; and WILMS TUMOR. It is caused by a mutation in the Wilms tumor suppressor gene (GENES, WILMS TUMOR) on chromosome 11.
Entry Term(s): Drash Syndrome; Nephropathy, Wilms Tumor, and Genital Anomalies; Pseudohermaphroditism, Nephron Disorder and Wilms' Tumor; Wilms Tumor and Pseudohermaphroditism
Previous Indexing: Nephroblastoma (1991-2001); Pseudohermaphroditism (1991-2001)
See Also: Genes, Wilms Tumor
Public MeSH Note: 2002
History Note: 2002
Date Established: 2002/01/01
Date of Entry: 2001/08/03
Revision Date: 2021/06/30

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Neoplasms [C04]
- Neoplasms by Histologic Type [C04.557]
  - Neoplasms, Complex and Mixed [C04.557.435]
    - Wilms Tumor [C04.557.435.595]
      - Denys-Drash Syndrome [C04.557.435.595.220]
      - WAGR Syndrome [C04.557.435.595.950]

Neoplasms [C04]
- Neoplasms by Site [C04.588]
  - Urogenital Neoplasms [C04.588.945]
    - Urologic Neoplasms [C04.588.945.947]
      - Kidney Neoplasms [C04.588.945.947.535]
        
        Wilms Tumor [C04.588.945.947.535.585]
        
        Denys-Drash Syndrome [C04.588.945.947.535.585.220]
        
        WAGR Syndrome [C04.588.945.947.535.585.950]

Neoplasms [C04]
- Neoplastic Syndromes, Hereditary [C04.700]
  - Wilms Tumor [C04.700.900]
    - Denys-Drash Syndrome [C04.700.900.220]
    - WAGR Syndrome [C04.700.900.950]

Urogenital Diseases [C12]
- Female Urogenital Diseases and Pregnancy Complications [C12.050]
  - Female Urogenital Diseases [C12.050.351]
    - Urogenital Abnormalities [C12.050.351.875]
      - Disorders of Sex Development [C12.050.351.875.253]
        
        Disorder of Sex Development, 46,XY [C12.050.351.875.253.096]
        
        Androgen-Insensitivity Syndrome [C12.050.351.875.253.096.500]
        
        Denys-Drash Syndrome [C12.050.351.875.253.096.562]
        
        Frasier Syndrome [C12.050.351.875.253.096.624]
        
        Gonadal Dysgenesis, 46,XY [C12.050.351.875.253.096.687]
        
        Kallmann Syndrome [C12.050.351.875.253.096.750]
        
        WAGR Syndrome [C12.050.351.875.253.096.875]

Urogenital Diseases [C12]
- Female Urogenital Diseases and Pregnancy Complications [C12.050]
  - Female Urogenital Diseases [C12.050.351]
    - Urogenital Neoplasms [C12.050.351.937]
      - Urologic Neoplasms [C12.050.351.937.820]
        
        Kidney Neoplasms [C12.050.351.937.820.535]
        
        Wilms Tumor [C12.050.351.937.820.535.585]
        
        Denys-Drash Syndrome [C12.050.351.937.820.535.585.220]
        
        WAGR Syndrome [C12.050.351.937.820.535.585.950]

Urogenital Diseases [C12]
- Female Urogenital Diseases and Pregnancy Complications [C12.050]
  - Female Urogenital Diseases [C12.050.351]
    - Urologic Diseases [C12.050.351.968]
      - Kidney Diseases [C12.050.351.968.419]
        
        Kidney Neoplasms [C12.050.351.968.419.473]
        
        Wilms Tumor [C12.050.351.968.419.473.585]
        
        Denys-Drash Syndrome [C12.050.351.968.419.473.585.220]
        
        WAGR Syndrome [C12.050.351.968.419.473.585.950]

Urogenital Diseases [C12]
- Male Urogenital Diseases [C12.200]
  - Urogenital Abnormalities [C12.200.706]
    - Disorders of Sex Development [C12.200.706.316]
      - Disorder of Sex Development, 46,XY [C12.200.706.316.096]
        
        Androgen-Insensitivity Syndrome [C12.200.706.316.096.500]
        
        Denys-Drash Syndrome [C12.200.706.316.096.562]
        
        Frasier Syndrome [C12.200.706.316.096.624]
        
        Gonadal Dysgenesis, 46,XY [C12.200.706.316.096.687]
        
        Kallmann Syndrome [C12.200.706.316.096.750]
        
        WAGR Syndrome [C12.200.706.316.096.875]

Urogenital Diseases [C12]
- Male Urogenital Diseases [C12.200]
  - Urogenital Neoplasms [C12.200.758]
    - Urologic Neoplasms [C12.200.758.820]
      - Kidney Neoplasms [C12.200.758.820.750]
        
        Wilms Tumor [C12.200.758.820.750.585]
        
        Denys-Drash Syndrome [C12.200.758.820.750.585.220]
        
        WAGR Syndrome [C12.200.758.820.750.585.950]

Urogenital Diseases [C12]
- Male Urogenital Diseases [C12.200]
  - Urologic Diseases [C12.200.777]
    - Kidney Diseases [C12.200.777.419]
      - Kidney Neoplasms [C12.200.777.419.473]
        
        Wilms Tumor [C12.200.777.419.473.585]
        
        Denys-Drash Syndrome [C12.200.777.419.473.585.220]
        
        WAGR Syndrome [C12.200.777.419.473.585.950]

Urogenital Diseases [C12]
- Urogenital Abnormalities [C12.800]
  - Disorders of Sex Development [C12.800.316]
    - Disorder of Sex Development, 46,XY [C12.800.316.096]

Urogenital Diseases [C12]
- Urogenital Neoplasms [C12.900]
  - Urologic Neoplasms [C12.900.820]
    - Kidney Neoplasms [C12.900.820.535]
      - Wilms Tumor [C12.900.820.535.585]
        
        Denys-Drash Syndrome [C12.900.820.535.585.220]
        
        WAGR Syndrome [C12.900.820.535.585.950]

Urogenital Diseases [C12]
- Urologic Diseases [C12.950]
  - Kidney Diseases [C12.950.419]
    - Kidney Neoplasms [C12.950.419.473]
      - Wilms Tumor [C12.950.419.473.585]
        
        Denys-Drash Syndrome [C12.950.419.473.585.220]
        
        WAGR Syndrome [C12.950.419.473.585.950]

Urogenital Diseases [C12]
- Urologic Diseases [C12.950]
  - Urologic Neoplasms [C12.950.983]
    - Kidney Neoplasms [C12.950.983.535]
      - Wilms Tumor [C12.950.983.535.585]
        
        Denys-Drash Syndrome [C12.950.983.535.585.220]
        
        WAGR Syndrome [C12.950.983.535.585.950]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Congenital Abnormalities [C16.131]
  - Urogenital Abnormalities [C16.131.939]
    - Disorders of Sex Development [C16.131.939.316]
      - Disorder of Sex Development, 46,XY [C16.131.939.316.096]
        
        Androgen-Insensitivity Syndrome [C16.131.939.316.096.500]
        
        Denys-Drash Syndrome [C16.131.939.316.096.562]
        
        Frasier Syndrome [C16.131.939.316.096.624]
        
        Gonadal Dysgenesis, 46,XY [C16.131.939.316.096.687]
        
        Kallmann Syndrome [C16.131.939.316.096.750]
        
        WAGR Syndrome [C16.131.939.316.096.875]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Neoplastic Syndromes, Hereditary [C16.320.700]
    - Wilms Tumor [C16.320.700.900]
      - Denys-Drash Syndrome [C16.320.700.900.220]
      - WAGR Syndrome [C16.320.700.900.950]

Endocrine System Diseases [C19]
- Gonadal Disorders [C19.391]
  - Disorders of Sex Development [C19.391.119]
    - Disorder of Sex Development, 46,XY [C19.391.119.096]

Denys-Drash Syndrome Preferred

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