MeSH Browser

MeSH Heading: Fluorescence Recovery After Photobleaching
Tree Number(s): E05.196.712.516.600.393
Unique ID: D036681
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D036681
Scope Note: A method used to study the lateral movement of MEMBRANE PROTEINS and LIPIDS. A small area of a cell membrane is bleached by laser light and the amount of time necessary for unbleached fluorescent marker-tagged proteins to diffuse back into the bleached site is a measurement of the cell membrane's fluidity. The diffusion coefficient of a protein or lipid in the membrane can be calculated from the data. (From Segen, Current Med Talk, 1995).
Entry Term(s): FRAP (Fluorescence Recovery After Photobleaching); Fluorescence Photobleaching Recovery
Previous Indexing: Fluorescence (1976-2002)
Public MeSH Note: 2003
History Note: 2003
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2004/07/07

Allowable Qualifiers: classification (CL)

economics (EC)

ethics (ES)

history (HI)

instrumentation (IS)

methods (MT)

standards (ST)

statistics & numerical data (SN)

trends (TD)

veterinary (VE)

Concept UI: M0410438
Scope Note: A method used to study the lateral movement of MEMBRANE PROTEINS and LIPIDS. A small area of a cell membrane is bleached by laser light and the amount of time necessary for unbleached fluorescent marker-tagged proteins to diffuse back into the bleached site is a measurement of the cell membrane's fluidity. The diffusion coefficient of a protein or lipid in the membrane can be calculated from the data. (From Segen, Current Med Talk, 1995).
Terms: Fluorescence Recovery After Photobleaching Preferred Term
Term UI T477118
Date01/11/2002
LexicalTag NON
ThesaurusID NLM (2003); Fluorescence Photobleaching Recovery
Term UI T481640
Date02/12/2002
LexicalTag NON
ThesaurusID NLM (2003); FRAP (Fluorescence Recovery After Photobleaching)
Term UI T481641
Date02/12/2002
LexicalTag NON
ThesaurusID NLM (2003)

Fluorescence Recovery After Photobleaching MeSH Descriptor Data 2025