MeSH Browser

MeSH Heading: RNA 5' Terminal Oligopyrimidine Sequence
Tree Number(s): G02.111.570.080.689.687.275; G05.360.080.689.687.275; G05.360.340.024.340.137.785
Unique ID: D038641
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D038641
Scope Note: A regulatory sequence found in the 5' terminal regions of a variety of RNA species. The sequence starts with a CYTIDINE, which is followed by a stretch of 5 to 15 PYRIMIDINE NUCLEOTIDES. Messenger RNA that contains the 5' Terminal Oligo Pyrimidine tract is often referred to as 5' TOP mRNA. The sequence acts as a translational regulator and has been found in mRNAs for PEPTIDE ELONGATION FACTORS and RIBOSOMAL PROTEINS.
Entry Version: RNA 5 TERMINAL OLIGOPYRIMIDINE SEQ
Entry Term(s): 5' TOP Messenger RNA; 5' TOP Sequence; 5' TOP mRNA; RNA 5' Terminal Oligopyrimidine Regulatory Sequence
Public MeSH Note: 2003
History Note: 2003
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2013/07/09

Allowable Qualifiers: drug effects (DE)

ethics (ES)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M0416549
Scope Note: A regulatory sequence found in the 5' terminal regions of a variety of RNA species. The sequence starts with a CYTIDINE, which is followed by a stretch of 5 to 15 PYRIMIDINE NUCLEOTIDES. Messenger RNA that contains the 5' Terminal Oligo Pyrimidine tract is often referred to as 5' TOP mRNA. The sequence acts as a translational regulator and has been found in mRNAs for PEPTIDE ELONGATION FACTORS and RIBOSOMAL PROTEINS.
Terms: RNA 5' Terminal Oligopyrimidine Sequence Preferred Term
Term UI T484520
Date03/05/2002
LexicalTag ACX
ThesaurusID NLM (2003); RNA 5' Terminal Oligopyrimidine Regulatory Sequence
Term UI T484521
Date03/05/2002
LexicalTag ACX
ThesaurusID NLM (2003); 5' TOP Sequence
Term UI T484522
Date03/05/2002
LexicalTag ACX
ThesaurusID NLM (2003)

RNA 5' Terminal Oligopyrimidine Sequence MeSH Descriptor Data 2025