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Photobleaching MeSH Descriptor Data 2025


MeSH Heading
Photobleaching
Tree Number(s)
G02.740.680
Unique ID
D038761
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D038761
Scope Note
Light-induced change in a chromophore, resulting in the loss of its absorption of light of a particular wave length. The photon energy causes a conformational change in the photoreceptor proteins affecting PHOTOTRANSDUCTION. This occurs naturally in the retina (ADAPTATION, OCULAR) on long exposure to bright light. Photobleaching presents problems when occurring in PHOTODYNAMIC THERAPY, and in FLUORESCENCE MICROSCOPY. On the other hand, this phenomenon is exploited in the technique, FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING, allowing measurement of the movements of proteins and LIPIDS in the CELL MEMBRANE.
Previous Indexing
Photochemistry (1972-2002)
Public MeSH Note
2003
History Note
2003
Date Established
2003/01/01
Date of Entry
2002/07/03
Revision Date
2016/06/17
Photobleaching Preferred
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